Asthma Trial, Recruiting NCT07139899 Sponsor: Bastiaan Driehuys Condition: Asthma
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Asthma Trial, Recruiting

NCT07139899
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are willing and able to give written consent to participate in the study
  • You are between 18 and 65 years old
  • A doctor has diagnosed you with asthma for more than 1 year
  • You have had breathing tests (lung function tests) done within the last 30 days that met standard quality guidelines
  • People of all racial and ethnic backgrounds may participate
  • Your blood test shows a higher-than-normal level of a type of immune cell called eosinophils (above 300 cells/μL) (confirm with trial site)
  • You have a relatively limited smoking history (less than 10 pack years) (confirm with trial site)
  • You have not smoked, vaped, used cigars, or used marijuana in the last 3 months
  • You are about to start treatment for asthma with one of these three medicines as part of your regular care: dupilumab, tezepelumab, or benralizumab

Who may not be able to join:

  • You have had a respiratory (breathing) tract infection in the 4 weeks before your first study visit
  • Your body mass index (BMI) is over 30 at your first study visit
  • You have recently received a one-time injection (such as a joint injection) without waiting 4 weeks before your first study visit
  • You have visited the emergency room for asthma in the 4 weeks before joining, or at any point during the study
  • You have a serious ongoing health condition such as heart disease, cancer, uncontrolled diabetes, or another chronic lung disease
  • Your blood oxygen level is too low (below 90%) even when using supplemental oxygen through a nose tube
  • You have a positive pregnancy test at your first visit or at any point during the study
  • You have taken part in another clinical trial or used an experimental drug in the past 30 days, or plan to do so during this study
  • The study doctor does not think you will be able to complete all parts of the study
  • The study doctor believes taking part would put you at too much risk
  • You have a condition that prevents you from safely having an MRI scan (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: David Mummy, PhD, Duke University

Phone: 9846847783

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Bastiaan Driehuys
Registry
ClinicalTrials.gov
Start date
17 November 2025
Est. completion
1 November 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Ventilation Defect in Mucus-blocked regions

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov