Osteoarthritis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are over 40 years of age
- People who have been diagnosed with moderate knee joint wear-and-tear (specifically graded 2–3 on a standard medical scale called the Kellgren-Lawrence score), and whose doctor has already recommended knee replacement surgery
- People whose knee condition includes signs of inflammation, such as pain at night, pain while resting, or repeated episodes of swelling, fluid build-up, or redness in the knee
- People who have persistent moderate or severe knee pain, measured above 4 on a standard 10-point pain scale
- People who have tried non-surgical treatments for at least 3 months without enough relief — these treatments may include physiotherapy, anti-inflammatory or pain-relief medications, or injections such as hyaluronic acid, corticosteroids, or similar therapies
- People who have signed a consent form agreeing to take part in the trial
- People whose case has been reviewed and approved as eligible by an internal team of specialists at the trial site
Who may not be able to join:
- People who are not able to make their own medical decisions
- People who have had a knee injury in the 6 months before the treatment
- People who have been diagnosed with a malignant cancer
- People who have a rheumatic disease (such as rheumatoid arthritis or similar conditions)
- People who are taking blood-thinning or anti-clotting medications — this applies even if the medication could be stopped 5 days before treatment
- People who have issues with alcohol, drug, or medication misuse
- People who have had surgery on the affected knee within the past 12 months
- People whose blood clotting level (INR) is below 2 (confirm with trial site)
- People whose platelet count in their blood is below 30,000 (confirm with trial site)
- People whose kidneys are not functioning well enough, specifically a kidney filtration rate below 30ml/min (confirm with trial site)
- People who are pregnant
- People who have an allergy to iodinated contrast, which is a dye sometimes used in medical imaging
- People who are unable to have an MRI scan
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: +39 0516366836
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Reduction of pain (VAS score)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.