Phase 1 Prostate Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are able to understand what the study involves and are willing to sign a consent form agreeing to take part.
• Healthy men or women between 18 and 60 years of age (inclusive).
• People whose body weight falls within a healthy range for their height, specifically a BMI between 19 and 26 kg/m² (inclusive).
• People whose heart health checks, physical examination, chest X-ray, abdominal ultrasound, and heart tracing (ECG) results are normal, or show only minor findings considered not medically important.
• People whose blood and urine test results are within normal ranges, or show only minor findings considered not medically important.
• People who are able to communicate clearly with the study team and are willing to attend all required follow-up visits.
• People who agree to use effective birth control throughout the study and for 6 months after it ends — this applies to both women and men (confirm with trial site for accepted methods).

Who may not be able to join:

• People who experience claustrophobia or who are unable to tolerate imaging scans for any reason.
• People who have a history of epilepsy or seizures, not including childhood febrile seizures (seizures caused by fever in early childhood).
• People who have, or have had, ongoing health conditions affecting the heart, lungs, digestive system, kidneys or urinary tract, blood, nervous system, hormones, metabolism, or muscles and bones.
• People who have a history of, or currently have, a significant mental health condition.
• People who have a history of asthma or allergies.
• People who have a history of cancer.
• People who have any condition that the study doctor believes could affect how the study drug is absorbed or processed by the body, or could interfere with study results.
• People who have had surgery in the 3 months before the study starts, or who have surgery planned during the study period.
• People who have donated blood or lost a significant amount of blood (more than 400 mL) in the 3 months before the study starts or during the screening period.
• People whose veins are not suitable for the two separate lines needed for study drug administration and blood sampling.
• People who have a known allergy to any ingredient in the study drug.
• People who have taken any medicines — including prescription drugs, over-the-counter medicines, or herbal products — in the 14 days before the study drug is given.
• People who have taken part in another clinical drug trial within 4 weeks before the study drug is given, or within 5 half-lives of that other trial drug, whichever period is longer.
• People who have had a nuclear medicine imaging scan or radioactive treatment within 7 days before screening, or within 5 half-lives of the radioactive substance used, whichever is longer.
• Women who are pregnant or breastfeeding.
• People whose blood test results show certain infections (including hepatitis B, hepatitis C, syphilis, or HIV) that the study doctor considers clinically significant.
• People whose heart tracing (ECG) shows a specific measurement (QTc interval) longer than 450 milliseconds during screening.
• People who have had significant exposure to radiation through their work in the past 10 years (for example, more than 50 mSv per year), or who have been exposed to radioactive materials for treatment or research purposes.
• People who the study doctor believes, for any reason, would be unlikely to complete the study.

Important: Always verify eligibility with the trial site directly before applying.