Phase 2 Ovarian Cancer Trial, Recruiting NCT07158021 Sponsor: University of Michigan Rogel Cancer Center Condition: Ovarian Cancer
Back to Ovarian Cancer

Phase 2 Ovarian Cancer Trial, Recruiting

NCT07158021
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Women aged 18 or older
  • Women who are pre-menopausal or peri-menopausal, meaning they have had a period within the 12 months before or after their breast cancer diagnosis, or whose hormone test results show they are not yet post-menopausal
  • People who are planning to take a hormone-suppressing injection (GnRHa) together with a hormone-blocking tablet (tamoxifen, anastrozole, exemestane, or letrozole) to treat stage 1–3 breast cancer or breast cancer that has spread to other parts of the body
  • People who have previously used hormone-suppressing injections for reasons unrelated to cancer, or during chemotherapy
  • People who are not planning to have both ovaries and fallopian tubes surgically removed during the 6-month study period
  • People who have finished chemotherapy if it was part of their treatment (certain other ongoing treatments, such as trastuzumab, pertuzumab, bone-strengthening medication, or some targeted cancer therapies, are permitted at the same time)
  • People who are able to understand and sign a consent form agreeing to take part in the study

Who may not be able to join:

  • People who have already had both ovaries and fallopian tubes surgically removed
  • People who are pregnant or breastfeeding (a pregnancy test will be checked before the study begins)
  • People who are currently using estrogen products applied to the skin or taken throughout the body
  • People with a known allergy or sensitivity to the medications goserelin or leuprolide, or to any of the ingredients in those medications
  • People who are unable to swallow or take tablets by mouth
  • People who have a medical condition that would affect how their body absorbs hormone-blocking tablets (confirm with trial site)
  • People who have had, or currently have, another type of cancer where the cancer itself or its treatment could affect how safely or accurately this trial can be assessed, in the opinion of the treating doctor

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Norah L Henry, University of Michigan Rogel Cancer Center

Phone: 1-800-865-1125

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
University of Michigan Rogel Cancer Center
Registry
ClinicalTrials.gov
Start date
22 January 2026
Est. completion
1 January 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Proportion of participants with ultrasensitive estradiol concentration > 10 pg/ml

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov