Phase 1 Alzheimer's Disease Trial, Recruiting NCT07158905 Sponsor: Institute for Molecular Medicine Condition: Alzheimer's Disease
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Phase 1 Alzheimer's Disease Trial, Recruiting

NCT07158905
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Men, or women who have gone through menopause or had a surgical procedure that means they can no longer become pregnant, aged between 65 and 80 years old
  • People whose thinking and memory are currently normal (not showing signs of cognitive impairment), based on specific memory and thinking tests (confirm with trial site for exact test score requirements)
  • People whose blood test results show early signs of Alzheimer's-related protein buildup in the brain, even though no symptoms are present yet, as measured by a specific test called PrecivityAD2™
  • People with good enough vision and hearing to take part in all study activities
  • People whose regular medications have been at a stable dose (if they take any), and who are willing to give written agreement to participate

Who may not be able to join:

  • People whose brain MRI scan shows certain abnormalities, such as signs of past strokes, more than five small bleeds in the brain, or other significant findings
  • People who cannot have an MRI scan for any reason, such as having a pacemaker, certain metal implants in the body, or severe fear of enclosed spaces
  • People who have had a serious illness or been hospitalised in the four weeks before joining the trial
  • People with significant heart, hormonal, blood, immune system, or neurological conditions
  • People with insulin-dependent diabetes, significant heart rhythm problems, or a history of seizures
  • People who have scored at a certain level or above on a suicide risk assessment questionnaire (confirm with trial site for details)
  • People who have received a treatment targeting tau or amyloid-beta proteins (two proteins linked to Alzheimer's disease) within the past year
  • People taking medications that suppress the immune system or prevent blood clotting, if those medications could affect safety in the trial
  • People with significant abnormal results on routine blood tests, or people who test positive for HIV, hepatitis B, or hepatitis C

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Michael Agadjanyan, PhD, Institute MM

Phone: 7145963981

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Institute for Molecular Medicine
Registry
ClinicalTrials.gov
Start date
23 June 2026
Est. completion
15 June 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Incidence of Treatment-Emergent Adverse Events (TEAEs) and Serious Adverse Events (SAEs)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov