Phase 2 Macular Degeneration Trial, Recruiting NCT07160179 Sponsor: AbbVie Condition: Macular Degeneration
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Phase 2 Macular Degeneration Trial, Recruiting

NCT07160179
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For both parts of the trial (Stage 1 and Stage 2):

  • People who have been diagnosed with geographic atrophy (a condition where patches of cells in the back of the eye break down) caused by age-related macular degeneration, in the eye being studied.

For Stage 1 only:

  • People whose area of eye damage meets a minimum size requirement (at least 0.5 DA, a unit used to measure damage on the retina), whether or not the damage is in the central part of the eye, as confirmed by the investigating doctor and a specialist reading centre before the study begins.
  • People who do not have abnormal blood vessel growth (called choroidal neovascularization) in the eye being studied, as confirmed by the investigating doctor and a specialist reading centre before the study begins.

For Stage 2 only:

  • People whose area of eye damage falls within a specific size range (between 1 and 7 DA) and is located in a particular zone near — but not yet affecting — the central part of the eye, as confirmed by the investigating doctor and a specialist reading centre before the study begins.
  • People who do not have abnormal blood vessel growth in either eye, as confirmed by the investigating doctor and a specialist reading centre before the study begins.

Who may not be able to join:

  • People who have a history of repeated or currently active inflammation inside or around the eye (such as uveitis or endophthalmitis) in at least one eye.
  • People who have an active infection in or around either eye at the time the study begins.
  • People who have a history of, or signs of, diabetic eye disease or any disease affecting the blood vessels of the retina — other than age-related macular degeneration — in at least one eye.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: ABBVIE INC., AbbVie

Phone: 844-663-3742

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Registry
ClinicalTrials.gov
Start date
13 August 2025
Est. completion
1 October 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Number of Participants Experiencing Adverse Events; Number of Participants with Abnormal Change in Physical Examinations; Number of Participants with Abnormal Change From Baseline in Vital Sign Measurements; Change From Baseline in Electrocardiograms (ECGs); Number of Participants with Abnormal Change in Clinical Laboratory Test Results Like Hematology will be Assessed; Change from baseline in Best Corrected Visual Acuity (BCVA); Change in Slit lamp biomicroscopy assessment; Change in Intraocular pressure (IOP); Change in Lens examination assessment; Change in Ophthalmoscopy assessment; Change...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov