Phase 2 Lymphoma Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with Angioimmunoblastic T-Cell Lymphoma (AITL) based on standard medical classification guidelines, and who have at least one area of disease that can be measured on scans (a swollen lymph node larger than 1.5 cm, or a growth outside the lymph nodes larger than 1.0 cm)
• People who have never received any previous treatment for this condition, including chemotherapy or radiation
• People aged 18 or older, of any gender, who are reasonably functional in daily life (confirm with trial site regarding the specific activity level scale used)
• People who are expected to live for more than 3 months
• People who are willing and able to attend follow-up appointments and understand what taking part in the study involves

Who may not be able to join:

• People with abnormal liver or kidney function test results more than twice the normal level, unless the trial site determines those results are caused by the lymphoma itself
• People whose bone marrow is not producing enough blood cells (low white blood cells, low platelets, or low haemoglobin), unless the trial site determines this is caused by the lymphoma affecting the bone marrow
• People who have previously had any local or systemic cancer treatment
• People with significant heart problems, including severe heart failure, a weakened pumping function of the heart, or certain heart conditions (such as heart attack, serious irregular heartbeat, or a history of abnormal heart rhythm) occurring within the past 6 months
• People with HIV/AIDS, syphilis, active hepatitis B, or hepatitis C
• People who have another cancer that is not well controlled, or another blood disorder such as haemophilia or myelofibrosis, where the treating doctor considers enrolment unsuitable
• People with a history of autoimmune disease, or who are currently taking immune-suppressing medication above a certain dose or for more than 2 weeks (confirm with trial site for specific details)
• People with an active infection that is not responding to treatment
• People with an uncontrolled condition called haemophagocytic syndrome, where the immune system attacks the body's own cells
• People who have had a significant surgical procedure within 3 weeks before starting treatment
• People who have taken part in another clinical drug trial within the past 30 days, or who are currently enrolled in another trial of a new drug
• People who are pregnant, breastfeeding, or of childbearing age and unwilling to use contraception during the trial
• People who are known to be allergic to any ingredients in the trial medication
• People whom the treating doctor considers unsuitable for enrolment for any other reason

Important: Always verify eligibility with the trial site directly before applying.