Crohn's Disease and Colitis Trial, Recruiting NCT07168499 Sponsor: Massachusetts General Hospital Condition: Crohn's Disease and Colitis
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Crohn's Disease and Colitis Trial, Recruiting

NCT07168499
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are able to give written consent and are willing to follow the study requirements
  • People who are 18 years of age or older
  • People who have been diagnosed with Crohn's disease, ulcerative colitis, or IBD-unspecified
  • People who have had recent evidence (within the last 6 months) of active IBD, shown through a colonoscopy, intestinal ultrasound, a scan, or raised inflammation levels in a blood test
  • People whose doctor is planning to start them on an advanced IBD medication (such as a biologic or similar treatment) within 2 weeks of joining the study, as part of their normal care
  • People whose other non-biologic IBD medications will stay the same during the study, with the only planned change being a gradual reduction of steroid medication if applicable
  • People whose IBD is currently active, based on a standard symptom score measured at the start of the study, or who have recently had a flare-up being treated with steroids

Who may not be able to join:

  • People who are unable or unwilling to give consent or are unlikely to follow the study requirements
  • People whose doctor is starting advanced therapy only to treat symptoms outside the gut (such as joint or skin symptoms), rather than gut symptoms
  • People who have a known eating disorder
  • People who are already receiving a specific dietary therapy or stress management program
  • People who have a serious untreated mental health condition, including a history of suicidal thoughts
  • People who have an untreated infection, such as a C. difficile gut infection
  • People who have a stoma (a surgically created opening in the abdomen) or a J-pouch (a surgically created internal pouch)
  • People who are pregnant, breastfeeding, or planning to become pregnant during the study
  • People who are receiving nutrition through an intravenous drip (TPN) or who are already following a therapeutic diet specifically for IBD

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Ashwin Ananthakrishnan, MD, MPH, Massachusetts General Hospital

Phone: 617-724-7559

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
15 September 2025
Est. completion
1 May 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change marked by clinical remission of IBD

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov