Phase 3 study for people with Alzheimer's Disease

Recruiting Phase 3

Sources: ClinicalTrials.gov Checked: 15 October 2026 Not medical advice

This trial at a glance

Status Recruiting
Phase Phase 3
Sponsor Hoffmann-La Roche
Registry number NCT07177352
Started 2 July 2025 Today 16 October 2026 Estimated completion 31 July 2035

Where this trial is running

Trial sites and the status recorded for each
SiteCityState or countryStatus at this site
Royal Prince Alfred Hospital Camperdown NSW Recruiting
St Vincent's Hospital Sydney Darlinghurst NSW Recruiting
Southern Neurology Kogarah NSW Recruiting
KaRa Institute of Neurological Diseases Macquarie Park NSW Recruiting
Flinders Medical Centre Bedford Park SA Recruiting
Queen Elizabeth Hospital Woodville SA Recruiting
Box Hill Hospital Box Hill VIC Recruiting
Heidelberg Repatriation Hospital Heidelberg VIC Recruiting
Alfred Health Melbourne VIC Recruiting
Royal Melbourne Hospital Parkville VIC Recruiting

voxsanity.com.au · trial sites from public registries · registry record synced 15 October 2026 · not medical advice

Who can join

Age 50 Years to 90 Years
Sex Anyone, regardless of sex
Healthy volunteers Not accepted
Enrolment target 80000

The official eligibility criteria

Registry text, reproduced exactly. These are the words the trial's sponsor published on ClinicalTrials.gov. They have not been edited, shortened or rewritten, and they are written for researchers rather than for patients.

Inclusion Criteria:

* Ability and willingness to participate in an interventional clinical study, including meeting key eligibility criteria of linked interventional Roche AD studies (e.g., specific age ranges)

* Ability and willingness to receive information about potential eligibility in an associated interventional Roche AD study

Exclusion Criteria:

* Dependency in basic activities of daily living (bADLs) due to cognitive impairment

* Visual or auditory impairment that would prevent them from performing the cognitive assessments (eyeglasses and hearing aids are permitted)

* Any self-reported evidence or known diagnosis of a neurological or neurodegenerative condition that may lead to cognitive impairment other than AD

* History of severe, clinically significant central nervous system trauma

* Any serious medical condition that precludes a participant's safe participation and completion of a clinical study

* For participants with a clinical diagnosis of MCI or mild AD: Previous AD diagnosis based on biomarker confirmation with an approved or validated rule in method (e.g., amyloid PET or cerebrospinal fluid, blood biomarker) is exclusionary

Dates on the record

Started 2 July 2025
Estimated completion 31 July 2035
Registry last updated 15 October 2026
Checked by Voxsanity 15 October 2026

Results, publications and the official record

Sources and dates

  • ClinicalTrials.gov – the record this page reformats
  • ClinicalTrials.gov processing date: 15 October 2026.
  • This page last checked by Voxsanity: 15 October 2026.

Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.

Not medical advice.

Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.

Letter for your doctor

A one-page summary of this trial to print or email to your GP. It carries the registry's own record of the trial and its eligibility criteria, and nothing Voxsanity has written about whether it suits you.