Macular Degeneration Trial, Recruiting NCT07178639 Sponsor: Nemocnice Kolín Condition: Macular Degeneration
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Macular Degeneration Trial, Recruiting

NCT07178639
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 or older (male or female) who need cataract surgery with no other surgical procedures performed at the same time
  • People who agree not to have any other eye surgery in either eye within 15 days before the study treatment starts, or at any point during the study
  • People whose best vision with glasses or contact lenses is at least 20/200 in either eye
  • People who are able to apply the study eye drops themselves, or who have a caregiver available to apply all doses for them

Who may not be able to join:

  • People with a known allergy or sensitivity to bromfenac, nepafenac, diclofenac, or any ingredient in the study treatment, including numbing drops, dilating drops, or fluorescein dye
  • People who have inflammation inside the eye being studied, detected at the screening visit
  • People with certain blood disorders, bone marrow problems, uncontrolled stomach ulcers, inflammatory bowel disease, ulcerative colitis, or uncontrolled/unstable lung, heart, blood vessel, autoimmune, liver, kidney, or nervous system conditions
  • People who have used certain anti-inflammatory medications (NSAIDs) or specific eye or body medications (gentamicin or cyclosporine eye drops) within 7 days before the study starts or during the study — though low-dose aspirin (81 mg or less per day) on a stable dose is allowed
  • People who have diabetes of any type
  • People who have any problems at the back of the eye where the vitreous meets the retina, as seen on a special eye scan
  • People who have previously had a specific type of eye surgery (pars plana vitrectomy) in the eye being studied
  • People with certain types of glaucoma, including any secondary glaucoma, closed-angle glaucoma, or severe open-angle glaucoma
  • People who have used certain eye pressure-lowering drops called prostaglandins within 30 days before the study starts or during the study
  • People who have active corneal (front of the eye) problems in the study eye at the screening visit, including a specific condition called superficial punctate keratitis
  • People who have any inflammation around or inside the study eye at the screening visit — mild eyelid inflammation (blepharitis) may be acceptable, but not if combined with conjunctivitis or eyelid swelling/redness; people with ongoing, unresolved uveitis are also not eligible
  • People who have used steroid medications — in any form including eye drops, inhaled, or tablets — within 14 days before the screening visit
  • People with a history of alcohol or drug misuse within the 6 months before the screening visit
  • People who are pregnant or currently breastfeeding
  • People who have taken part in another clinical trial of an investigational drug or device within 30 days before being enrolled in this study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +420728872150

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Nemocnice Kolín
Registry
ClinicalTrials.gov
Start date
1 August 2025
Est. completion
28 February 2026

Where this trial is recruiting

🇨🇿 Czechia

Primary endpoints

Cystoid macular oedema presence

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov