Restless Legs Syndrome Trial, Recruiting NCT07179406 Sponsor: University of Alabama at Birmingham Condition: Restless Legs Syndrome
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Restless Legs Syndrome Trial, Recruiting

NCT07179406
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with Restless Legs Syndrome (RLS)
  • Your RLS medications have not changed significantly in the past 4 weeks
  • You are willing and able to follow the study's rules and schedule
  • You are a healthy person without RLS (for the healthy comparison group in the study)
  • You are able to understand and sign a consent form agreeing to take part

Who may not be able to join:

  • You have a mental or physical condition that would stop you from completing the study activities
  • You are currently using a device (such as a wearable or medical device) to treat your RLS
  • You are not willing or able to follow the study's rules and schedule
  • You have another medical condition that the study doctor believes could put you at risk
  • You are pregnant, breastfeeding, or trying to become pregnant
  • You are currently taking part in, or planning to join, another clinical study that might affect your RLS
  • You have any of the following conditions: spinal cord injury, severe nerve damage or nerve root problems, a serious psychiatric or memory/thinking disorder, a history of drug or alcohol abuse in the past year, epilepsy or seizures, an active or ongoing infection (other than a common cold), a cancer diagnosis within the past 5 years (excluding certain minor skin cancers), a severe movement disorder such as Parkinson's disease, deep vein thrombosis (a blood clot in a vein), or multiple sclerosis

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 2059343411

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
4 August 2025
Est. completion
31 January 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Changes in H-reflex neurophysiological activity in response to Spinal Cord Stimulation (SCS); Changes in Somatosensory Evoked Potential (SSEP) activity in response to Spinal Cord Stimulation (SCS); Changes in Vibratory Electrophysiological Response Potential (ERP) activity in response to Spinal Cord Stimulation (SCS); Changes in Transcranial Magnetic Stimulation (TMS) activity in response to Spinal Cord Stimulation (SCS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov