Motor Neurone Disease Trial, Recruiting NCT07179822 Sponsor: Medical University of South Carolina Condition: Motor Neurone Disease
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Motor Neurone Disease Trial, Recruiting

NCT07179822
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years old or older
  • You have a history of a spinal cord injury at the neck level (at or above the C6 vertebra)
  • Your spinal cord injury occurred more than 1 year ago and your condition has been neurologically stable since then
  • A doctor has cleared you to take part in this study
  • You have some weakness in at least one wrist when trying to bend it upward (wrist extension)
  • Your current medications are expected to stay the same for at least 3 months (note: stable use of muscle spasm medications such as baclofen, diazepam, or tizanidine is acceptable)

Who may not be able to join:

  • You have an injury to the motor nerve cells themselves (confirm with trial site)
  • You have an unstable medical condition
  • You have significant difficulties with thinking, memory, or understanding, since this study involves a learning-based treatment
  • You have a history of epileptic seizures
  • You have another existing neurological condition, such as multiple sclerosis, stroke, or Parkinson's disease
  • You have any metal implants in your skull
  • You have a medical device implanted in or above your chest, such as a pacemaker or cochlear implant
  • Specific nerve signal tests in your wrist muscles show no measurable response (confirm with trial site)
  • You are completely unable to produce any voluntary muscle activity in your wrist extensor muscles (confirm with trial site)
  • You use functional electrical stimulation on your arm every day on an extensive basis
  • You are pregnant
  • You or your legal representative are unable or unwilling to give informed consent to take part

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Aiko Thompson, PhD, Medical University of South Carolina

Phone: (843) 792-6313

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
3 November 2025
Est. completion
30 September 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Percent change in the size of the Motor Evoked Potential (MEP) from baseline to final conditioning sessions.; Change in Spinal Cord Independence Measure--version III (SCIM III) score

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov