Breast Cancer Trial, Recruiting NCT07180693 Sponsor: European Institute of Oncology Condition: Breast Cancer
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Breast Cancer Trial, Recruiting

NCT07180693
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People of any gender, aged 18 or older
  • People who have been diagnosed with a specific type of early-stage breast cancer (hormone receptor-positive, HER2-negative) that has been surgically removed, and whose doctors have recommended a type of medication called a CDK4/6 inhibitor (either abemaciclib or ribociclib) after surgery
  • People whose tumour testing shows specific hormone receptor levels and HER2 protein levels within defined ranges, as measured by laboratory tests according to standard guidelines (confirm with trial site)
  • People who are starting or have already started treatment with abemaciclib or ribociclib combined with hormone-blocking therapy, where that treatment began on or after 1 January 2021
  • People with a general health and activity level rated at 2 or below on a standard medical scale (meaning they are able to care for themselves, even if not able to do all physical activity)
  • People who agree to allow their personal data to be used according to local privacy rules

Who may not be able to join:

  • People currently taking part in another clinical study specifically for the same type of breast cancer (hormone receptor-positive, HER2-negative early breast cancer) involving experimental treatments
  • People who have previously received a CDK4/6 inhibitor as part of a clinical trial (as opposed to standard medical care)
  • People who are unable to follow the requirements of the study, or whom the study doctor considers unsuitable for inclusion
  • People with a history of a previous breast cancer diagnosis, unless it was a very early, non-invasive type (called DCIS) that was treated with local therapy only, and that treatment was completed at least 5 years ago
  • People with a history of any other type of cancer (other than certain common skin cancers or early-stage cervical changes), unless they have been in full remission with no cancer treatment for at least 5 years

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 6 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Nadia Bianco, MD, European Institute of Oncology

Phone: +39 02 94371977

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
European Institute of Oncology
Registry
ClinicalTrials.gov
Start date
29 September 2025
Est. completion
1 August 2028

Where this trial is recruiting

🇮🇹 Italy

Primary endpoints

Invasive-disease free survival (IDFS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov