Phase 1 Oesophageal Cancer Trial, Recruiting NCT07182149 Sponsor: Normunity AccelCo, Inc. Condition: Oesophageal Cancer
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Phase 1 Oesophageal Cancer Trial, Recruiting

NCT07182149
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed (through a tissue or cell sample) with one of the following advanced or metastatic cancers: non-small cell lung cancer (squamous or adenocarcinoma type), triple-negative breast cancer, head and neck squamous cell cancer, esophageal squamous cell cancer, esophageal adenocarcinoma, stomach or gastroesophageal junction adenocarcinoma, cervical cancer, endometrial cancer, or ovarian cancer.
  • People whose general health and ability to carry out daily activities is rated as fully active or restricted only in physically strenuous activity (this is measured on a standard scale used by doctors, called ECOG 0 or 1).
  • People whose liver, kidneys, lungs, and heart are functioning at an adequate level, as determined by the trial site.
  • People whose blood cell counts and related measures are at adequate levels, as determined by the trial site.

Who may not be able to join:

  • People who have received certain cancer treatments — including chemotherapy, biological therapies, checkpoint inhibitor drugs, or radiation therapy (other than radiation to bone only) — within approximately 3 weeks or 5 half-lives of the first trial dose, whichever is the shorter period.
  • People with a history of moderate lung inflammation (pneumonitis) that required steroid treatment, or any severe or life-threatening lung inflammation from a previous treatment.
  • People who have taken part in another clinical trial and received an investigational (experimental) treatment within approximately 4 weeks or 5 half-lives of the first trial dose, whichever is the shorter period.
  • People who still have significant side effects from previous cancer treatment that have not resolved — with the exception of hair loss, or mild-to-moderate nerve-related symptoms (such as tingling or numbness).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Viviana Bozon, MD, Normunity AccelCo, Inc.

Phone: 215-593-7119

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Normunity AccelCo, Inc.
Registry
ClinicalTrials.gov
Start date
30 October 2025
Est. completion
30 May 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Incidence of treatment-emergent adverse events (TEAE); Incidence of dose-limiting toxicities (DLTs)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov