Phase 3 Lung Cancer Trial, Recruiting NCT07185997 Sponsor: ArriVent BioPharma, Inc. Condition: Lung Cancer
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Phase 3 Lung Cancer Trial, Recruiting

NCT07185997
Recruiting Phase 3 🇦🇺 Australian site

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • You have been diagnosed with advanced or spreading non-small cell lung cancer (a common type of lung cancer) that cannot be treated with surgery or radiation to cure it, and this has been confirmed through a lab test on a tissue or cell sample.
  • Your lung cancer has been tested (either from a tumor sample or a blood test) and found to have a specific gene change called an "EGFR PACC mutation."
  • You have not yet received any drug treatments (such as chemotherapy, targeted therapy, or immunotherapy) for your advanced or spreading lung cancer.
  • If you previously had treatment (such as chemotherapy, immunotherapy, or combined chemo-radiation) for an earlier stage of lung cancer that had not spread, at least 12 months must have passed since that treatment ended before joining this trial.
  • You are eligible if you have cancer that has spread to the brain but is not causing any symptoms.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • You have previously received any targeted drug treatments aimed at the EGFR gene (such as EGFR inhibitor pills, certain antibody treatments, or similar therapies) for advanced or spreading lung cancer.
  • You have received any other type of systemic (whole-body) cancer drug treatment for advanced or spreading lung cancer.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 August 2026

Contact this trial

Principal Investigator: Jamuna Thimmarayappa, ArriVent BioPharm

Phone: (888) 622-2827

Australian sites

Blacktown Cancer and Haematology Centre, Blacktown, New South Wales
Chris O'Brien Lifehouse, Camperdown, New South Wales
GenesisCare North Shore Health Hub, St Leonards, New South Wales
Austin Health, Heidelberg, Victoria

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
ArriVent BioPharma, Inc.
Registry
ClinicalTrials.gov
Start date
17 December 2025
Est. completion
1 February 2029

Where this trial is recruiting

🇦🇺 Australia 🇨🇦 Canada 🇫🇷 France 🇬🇷 Greece Hong Kong 🇮🇹 Italy 🇯🇵 Japan 🇲🇾 Malaysia 🇸🇬 Singapore 🇰🇷 South Korea 🇪🇸 Spain 🇹🇼 Taiwan 🇹🇭 Thailand Turkey (Türkiye) 🇬🇧 United Kingdom 🇺🇸 United States

4 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Progression Free Survival (PFS) determined by blinded independent central review (BICR); Confirmed overall response rate (ORR) as determined by BICR

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 August 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov