NCT07185997

Who might be able to join this trial:

• You have been diagnosed with advanced or spreading non-small cell lung cancer (a common type of lung cancer) that cannot be treated with surgery or radiation to cure it, and this has been confirmed through a lab test on a tissue or cell sample.
• Your lung cancer has been tested (either from a tumor sample or a blood test) and found to have a specific gene change called an "EGFR PACC mutation."
• You have not yet received any drug treatments (such as chemotherapy, targeted therapy, or immunotherapy) for your advanced or spreading lung cancer.
• If you previously had treatment (such as chemotherapy, immunotherapy, or combined chemo-radiation) for an earlier stage of lung cancer that had not spread, at least 12 months must have passed since that treatment ended before joining this trial.
• You are eligible if you have cancer that has spread to the brain but is not causing any symptoms.

Who may not be able to join:

• You have previously received any targeted drug treatments aimed at the EGFR gene (such as EGFR inhibitor pills, certain antibody treatments, or similar therapies) for advanced or spreading lung cancer.
• You have received any other type of systemic (whole-body) cancer drug treatment for advanced or spreading lung cancer.

Important: Always verify eligibility with the trial site directly before applying.