Phase 2 Oesophageal Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 80 who have been diagnosed with esophageal squamous cell carcinoma (a specific type of oesophageal cancer) confirmed by laboratory testing of tissue samples
• People whose cancer cannot be surgically removed, has come back after surgery, or has spread to other parts of the body, and whose cancer has either stopped responding to or could not be tolerated with a first round of systemic (whole-body) cancer treatment
• People who have at least one tumour that can be measured on a scan, according to standard criteria used in cancer trials
• People whose blood counts and organ function (including blood cells, liver, kidneys, and heart) meet minimum health levels as tested before joining (confirm with trial site for specific values)
• People whose heart is pumping at a normal level, based on an ultrasound of the heart
• People whose general health and ability to carry out daily activities falls within an acceptable range on a standard medical scale (confirm with trial site)
• People who are expected to live for at least three more months
• People who are willing to take part voluntarily, sign a consent form, and follow the study's schedule and requirements

Who may not be able to join:

• People with serious failure of major organs, an active infection that is not under control, or other significant health conditions
• People who have cancer that has spread to the spine and is pressing on the spinal cord
• People who have an abnormal opening between the oesophagus and the airway or the chest cavity
• People who have fluid build-up around the lungs, heart, or pelvis that keeps returning and needs to be repeatedly drained
• People whose cancer is growing into the heart or major blood vessels, where the treating doctor considers there to be a serious risk of life-threatening bleeding
• People whose cancer is growing into the windpipe or airways, where the treating doctor considers there to be a risk of an abnormal opening forming between the oesophagus and airway
• People whom the treating doctor considers unsuitable for the specific type of focused, short-course radiation therapy used in this trial
• People who are pregnant or breastfeeding
• People with a diagnosed mental health disorder, or those with a history of misusing psychiatric medications and who are unable to stop
• People who have taken part in another drug clinical trial within the past four weeks
• People, or their families, who do not wish to participate in the study

Important: Always verify eligibility with the trial site directly before applying.