Phase 3 Macular Degeneration Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• The eye being studied has been diagnosed with intermediate age-related macular degeneration (a condition affecting central vision) according to standard medical criteria
• The eye being studied has at least one large deposit under the retina (called a drusen) measuring 125 micrometres or wider in the central area of the eye
• A Traditional Chinese Medicine (TCM) assessment has identified a specific pattern described as "Yang-hyperactivity due to Yin-deficiency" (confirm with trial site)
• People aged 45 to 85 years, of any gender
• The eye being studied has a measured vision level falling within a specific range — roughly between normal vision and moderately reduced vision (20/20 to 20/200 on a standard eye chart)
• Willingness to participate voluntarily and to sign an informed consent form

Who may not be able to join:

• The eye being studied has other eye conditions that could interfere with the trial, such as severe short-sightedness, glaucoma, diabetic eye disease, blocked retinal veins, eye inflammation, detached retina, optic nerve problems, or a hole in the macula
• The eye being studied has an eye pressure reading of 25 mmHg or higher
• There is an area of significant retinal tissue loss (geographic atrophy) affecting the central point of vision in the eye being studied
• The eye being studied has previously had certain surgeries, including vitrectomy or macular translocation surgery
• The eye being studied is missing its natural lens without a replacement, or has a ruptured lens capsule (with some exceptions — confirm with trial site)
• The eye being studied has had any eye surgery (other than injections into the eye) within the past 3 months that could affect trial results or imaging
• A cataract in the eye being studied that blocks a clear view of the back of the eye
• The eye being studied has received certain laser treatments within the 3 months before screening
• The person has received relevant Traditional Chinese Medicine treatment within 1 month before screening
• There is an active eye infection in either eye that affects examination or imaging
• The other eye (not being studied) has very poor vision below a certain level on the standard eye chart
• A known allergy to any of the medications or diagnostic substances used in the trial
• Blood pressure that remains poorly controlled (above certain levels) despite taking blood pressure medication
• Certain abnormal blood test results, including low platelet counts or elevated liver or kidney markers (confirm with trial site)
• People who are pregnant, breastfeeding, planning a pregnancy within six months, or unwilling to use effective contraception during the trial and for six months after finishing the study medication
• Serious uncontrolled health conditions, including severe psychiatric, neurological, breathing, immune system, blood, or heart conditions, or active cancer
• Participation in another clinical trial within the 3 months before this trial
• People considered unsuitable by the trial investigator for any reason

Important: Always verify eligibility with the trial site directly before applying.