Phase 2 Schizophrenia Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been formally diagnosed with schizophrenia as their primary psychiatric condition
- People whose schizophrenia has been in a stable, non-crisis phase for at least 8 weeks before the screening appointment, as judged by the study doctor
- People who have had a schizophrenia diagnosis for at least 1 year before the screening appointment
- People who have been taking a single antipsychotic medication (with any additional mental health medications) at the same stable dose for at least 2 months before screening
- People aged between 18 and 55 years old (male or female)
- People whose body weight falls within a healthy range, specifically a Body Mass Index (BMI) between 18 and 40 (confirm with trial site if unsure how to calculate this)
- People who the study doctor believes are able to follow all study procedures throughout the trial
- People who have read, understood, and signed a consent form before the screening process begins
Who may not be able to join:
- People who are currently being treated with more than one antipsychotic medication at the time of screening
- People who show certain movement-related side effects, measured by a standard rating scale called the Modified Simpson-Angus Scale, scoring 2 or higher on any individual item at screening (confirm with trial site)
- People who have a moderate to severe problem with substance use — this includes alcohol, but does not include nicotine or caffeine
- People who have an unstable or poorly controlled physical health condition
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
To evaluate the efficacy of KYN-5356 treatment on cognitive function in adults with cognitive impairment associated with schizophrenia (CIAS)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.