Phase 3 Interstitial Lung Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are 40 years of age or older at the time of signing the consent form.
• You have at least one close blood relative (a parent, brother, sister, or child) who has been diagnosed with a form of pulmonary fibrosis (scarring of the lungs), including IPF, NSIP, or a genetically caused lung scarring condition.
• A special type of CT scan (a high-resolution CT) has shown signs of early changes or abnormalities in at least a portion of one of your lungs.
• Your lungs are able to hold and move air at a reasonably normal level (at least 80% of what would be expected for someone your age and size), based on a breathing test.
• Your lungs are able to transfer oxygen into your blood at a reasonably normal level (at least 70% of what would be expected), based on a breathing test.
• Additional inclusion criteria may apply (confirm with trial site).

Who may not be able to join:

• You already have a known pulmonary fibrosis diagnosis that your doctor believes needs to be treated with approved medications.
• A breathing test shows a certain pattern suggesting your airways may be obstructed or narrowed (confirm with trial site).
• Your CT scan shows signs of a specific pattern of lung scarring called "usual interstitial pneumonia" (UIP) that looks probable or definite.
• You have a medical condition known to cause lung scarring, such as a connective tissue disease (for example, rheumatoid arthritis or lupus).
• You have previously taken or are currently taking any of these medications: nerandomilast, nintedanib, or pirfenidone.
• Additional exclusion criteria may apply (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.