Phase 2 Breast Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults aged 18 or older.
- People who have been diagnosed with locally advanced, inoperable, or metastatic (spread to other parts of the body) breast cancer. People with high-risk HER-2 positive breast cancer who have finished pre-surgery chemotherapy and whose doctor determines they need a specific follow-up treatment (Enhertu) may also be considered.
- People who have already received 3 or 4 rounds of a treatment called Enhertu, and whose doctor expects them to continue that treatment for at least another 12 weeks. (Being on additional HER-2 targeted treatments alongside Enhertu is also permitted.)
- People who are able and willing to take part in guided aerobic exercise (such as walking or cycling) and resistance exercise (such as weights or body-weight exercises) as part of the trial.
- People who are currently following the standard contraception (birth control) requirements for their treatment, and who are willing to continue doing so for the full length of the trial.
- People who are able to understand the study information and are willing to sign a consent form that meets required guidelines.
- People who, in the opinion of the trial doctor, are experiencing noticeable fatigue (tiredness) related to their condition or treatment.
- People who have completed a standard exercise health screening process and are considered fit to participate in the study by the trial doctor.
Who may not be able to join:
- People who are already meeting national physical activity guidelines for both resistance training and aerobic exercise — meaning they are already doing structured resistance training (using weights, bands, or body weight, such as squats or push-ups) on 2 or more days per week, AND already doing 150 or more minutes per week of moderate-intensity aerobic activity (activity where a person can talk but not sing, such as walking, swimming, or cycling).
- People who have medical, mental health, cognitive, or other conditions that may make it difficult to understand the study information, give informed consent, or follow the study requirements fully.
- People who are taking certain medications that are not permitted in this trial (confirm specific medications with the trial site).
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 801-585-0571
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in Functional Assessment of Chronic Illness Therapy (FACIT) Fatigue score from baseline to Week 13 (end of exercise intervention).
Can't join this trial?
Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.