Phase 2 Macular Degeneration Trial, Recruiting NCT07215234 Sponsor: Sanofi Condition: Macular Degeneration
Back to Macular Degeneration

Phase 2 Macular Degeneration Trial, Recruiting

NCT07215234
Recruiting Phase 2 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 60 years old or older
  • You have been diagnosed with geographic atrophy (GA) caused by age-related macular degeneration (AMD)
  • The vision in your study eye (the eye being treated) meets specific vision test score ranges depending on which part of the trial you are joining (confirm with trial site)
  • The area of vision loss in your study eye falls within a specific size range, depending on which part of the trial you are joining; if you have multiple affected areas, at least one must be above a minimum size (confirm with trial site)

Who may not be able to join:

  • Your GA is caused by something other than AMD
  • You have abnormal blood vessel growth in the study eye, or have ever been treated with certain injections (anti-VEGF) in that eye
  • You have any eye condition, treatment, or surgery history that could affect vision improvement or interfere with the study assessments (confirm with trial site)
  • You are currently using, or have used in the past 12 months, any medication that targets a part of the immune system called the complement system
  • You have used certain steroid treatments in or around the study eye within specific time periods before joining (confirm with trial site)
  • You have had certain laser, light-based, or heat-based treatments in the study eye
  • You had an active eye infection in the study eye within the past 6 months
  • You currently have an active infection in or around either eye
  • You have glaucoma in the study eye that is active and not well controlled
  • You have ever had inflammation inside the eye (uveitis) or of the outer eye wall (scleritis) in either eye
  • You have previously received gene therapy in either eye
  • You have a serious ongoing health condition that would make it difficult to follow the trial schedule and requirements

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 800-633-1610

Australian sites

Investigational Site Number : 0360003, Sydney, New South Wales
Investigational Site Number : 0360002, Adelaide, South Australia
Investigational Site Number : 0360001, East Melbourne, Victoria

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Registry
ClinicalTrials.gov
Start date
9 October 2025
Est. completion
13 October 2027

Where this trial is recruiting

🇦🇺 Australia 🇺🇸 United States

3 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Incidence and severity of ocular and non-ocular treatment-emergent adverse events (TEAEs); Incidence and severity of ocular and non-ocular treatment-emergent serious adverse events (TESAEs)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov