Phase 4 Stroke Trial, Recruiting NCT07220538 Sponsor: Dr. Willmar Schwabe GmbH & Co. KG Condition: Stroke
Back to Stroke

Phase 4 Stroke Trial, Recruiting

NCT07220538
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 55 or older who have agreed to take part by giving their informed consent
  • People who have had a mild acute ischemic stroke (a stroke caused by a blood clot) that did not cause significant disability, confirmed by an MRI scan, and which occurred at least 7 days but no more than 14 days before the start of the study
  • People who show some level of cognitive impairment (mild difficulties with memory or thinking), based on a specific scoring test called the MoCA, with the cut-off score depending on how many years of education the person has had
  • People with sufficient Chinese language skills to understand and answer interview questions, complete questionnaires, and take part in thinking and memory tests

Who may not be able to join:

  • People who are currently taking part in, or have taken part in, another experimental drug trial within the past 4 weeks
  • People with communication difficulties such as trouble speaking, understanding language, or significant vision or hearing loss that could affect their ability to take part in the study or complete cognitive tests
  • People who had cognitive impairment or dementia (such as Alzheimer's disease, vascular dementia, Lewy body dementia, or frontotemporal dementia) before their stroke
  • People whose stroke was caused by a heart condition, or who have atrial fibrillation (an irregular heartbeat), or any condition that requires them to take blood-thinning medication (anticoagulants)
  • People who needed clot-dissolving medication (thrombolytics) on the day of screening or the first study visit
  • People whose stroke involved any bleeding into the brain (hemorrhagic transformation)
  • People who are currently taking traditional Chinese medicines
  • People with a serious neurological condition, including (but not limited to): bleeding in the brain, delirium, Parkinson's disease, brain tumour, brain damage from alcohol, brain infections, epilepsy, recent head injury, subdural hematoma, HIV-related cognitive problems, Huntington's disease, or several other specified brain conditions
  • People with major depression or generalised anxiety disorder
  • People with an active cancer diagnosis
  • People with alcohol addiction or substance abuse problems
  • People with a known allergy or sensitivity to Ginkgo biloba, Ginkgo biloba extract, or any ingredient in the trial medication
  • People who would not be able to attend follow-up visits at the required times — including those in long-term hospital care or full nursing home care where they are bedridden and require general nursing assistance (confirm with trial site regarding specific living situations)
  • People with a serious illness where life expectancy is less than 12 months

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Principal Investigator: Petra Klement, Dr. Willmar Schwabe GmbH & Co. KG

Phone: +497214009583

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Sponsor
Dr. Willmar Schwabe GmbH & Co. KG
Registry
ClinicalTrials.gov
Start date
28 November 2025
Est. completion
31 December 2027

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Change in Montreal Cognitive Assessment (MoCA) Total Score; Change in Cognitive Function Using Trail Making Test (TMT) Parts A and B; Change in Cognitive Processing Speed Using Symbol Digit Modalities Test (SDMT); Change in Verbal Fluency Performance Using Verbal Fluency Test (VFT); Change in Clinical Global Impression of Change Using ADCS-CGIC (Alzheimer's Disease Cooperative Study - Clinical Global Impression of Change); Change in Neurological Impairment Using National Institutes of Health Stroke Scale (NIHSS); Change in Neurological Impairment Using Modified Rankin Scale (mRS); Any new stro...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov