Prostate Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed with prostate cancer confirmed by a laboratory test of tissue samples
- People aged 18 years or older
- People who are fully active or have only minor restrictions in physical activity (this is measured by a standard scale called ECOG; scores 0–1 are required — confirm with trial site if unsure)
- People who are able to understand the study information and are willing to sign a consent form agreeing to take part
- People who are willing to provide several blood samples during the study
- People who are willing to provide tumour tissue samples (from surgery or biopsy, depending on which part of the trial they join) so researchers can compare different ways of detecting cancer
- Primary group: People with high-risk prostate cancer that has not spread beyond the local area, meeting one or more specific medical criteria related to cancer stage, tumour grade, and a blood marker called PSA (confirm exact thresholds with trial site); the treating surgeon must consider surgery appropriate
- Exploratory group: People with a prostate cancer diagnosis who fall into one of these categories: cancer being monitored without active treatment (active surveillance), cancer that has returned after previous treatment, cancer that has spread but still responds to hormone treatment, or cancer that has spread and no longer responds to hormone treatment
Who may not be able to join:
- People who have had another type of cancer diagnosed within the last 3 years (certain common skin cancers may be an exception — confirm with trial site)
- People who are currently receiving hormone-blocking therapy or other systemic (whole-body) treatments for prostate cancer
- People whose medical condition or personal circumstances may make it difficult to follow the study requirements
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Leonard J Appleman, MD, PhD, UPMC Hillman Cancer Center
Phone: 4126478258
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
ctDNA detection
Can't join this trial?
Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.