Phase 3 Osteoarthritis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are male or female and aged 40 years or older
- People whose body weight falls within a specific range based on their height (confirm with trial site for exact BMI limits)
- People who have ongoing knee pain caused by osteoarthritis
- People whose osteoarthritis has been graded as mild (Grade 2) or moderate (Grade 3) on a standard medical scale called the Kellgren-Lawrence scale
- People whose knee pain scores meet a specific level at the start of the trial, measured using a standard knee pain questionnaire called the KOOS (confirm with trial site for exact score requirements)
- People who are currently taking pain relief medication on a regular basis
- People who have responded in a specific way to a diagnostic nerve block procedure (a test injection used to identify the source of pain)
- People who are able and willing to follow all the requirements of the study
Who may not be able to join:
- People who have a type of arthritis caused by inflammation rather than wear and tear (such as rheumatoid arthritis)
- People who have other conditions or factors that could affect the trial results (confirm with trial site for specifics)
- People who have had a lower limb amputation
- People who have previously received certain treatments for their knee condition (confirm with trial site for specifics)
- People who have certain physical or psychological health conditions (confirm with trial site for specifics)
- People whose scores on a mental health questionnaire called the Patient Health Questionnaire fall outside acceptable limits (confirm with trial site for specifics)
- People who have moderate to severe liver problems
- People who have moderate to severe kidney problems
- People who are taking certain medications at the start of the trial (confirm with trial site for specifics)
- People who are unlikely to be able to follow the study's rules and schedule (confirm with trial site for specifics)
- People who have known allergies or sensitivities to certain substances used in the trial (confirm with trial site for specifics)
- People who have a history of alcohol or drug misuse
- People who have certain abnormal results on heart (ECG) tests or abnormal vital signs (such as blood pressure or heart rate) during the screening process, as determined by the investigator
- People who have certain abnormal results on blood or other laboratory tests at the start of the trial
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 770-274-2827
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change From Baseline to Week 12 in the Weekly Mean of the Average Daily Pain Intensity While Walking
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.