Alzheimer's Disease Trial, Recruiting NCT07226674 Sponsor: University of Ulster Condition: Alzheimer's Disease
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Alzheimer's Disease Trial, Recruiting

NCT07226674
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 50 years or older
  • People with a body mass index (a measure of body weight relative to height) of 25 or above
  • People who have a parent, sibling, or child who has been diagnosed with Alzheimer's disease
  • People who regularly eat a typical Western-style diet, meaning one that is high in animal products, refined carbohydrates, and processed foods
  • People who are willing and able to follow the study procedures and sign a written consent form

Who may not be able to join:

  • People who show signs of cognitive impairment or memory difficulties at the time of joining, as measured by specific memory and thinking tests (confirm with trial site)
  • People who have a pre-existing psychosis or other psychiatric condition
  • People who are currently receiving treatment for dementia
  • People with a history of substance abuse or a stroke or other blood vessel-related brain event
  • People who smoke more than half a pack of cigarettes per day
  • People with a known or suspected intolerance or allergy to any ingredient in the study products
  • People who have taken probiotics or antibiotics within the last month
  • People whose medications have changed in the last three months
  • People who are frail, malnourished, or have a food allergy or intolerance that requires a special diet
  • People who are already following a specific diet, such as a vegetarian or vegan diet
  • People who weigh more than 400 pounds, due to the weight limit of the MRI scanning table used in the study
  • People who are pregnant, breastfeeding, less than six months postpartum, or unwilling to use birth control during the study
  • People who cannot safely have an MRI scan, for example due to claustrophobia or having a pacemaker, neurostimulator, or metal implant in their body
  • People who live with chronic pain
  • People with any condition that, in the opinion of the study doctor, could affect their safety or the reliability of the study results
  • People who are unable to sign a consent form due to psychological or language barriers
  • People who are under legal guardianship or whose rights are restricted by an administrative or legal decision
  • People who are currently taking part in another medical research study, or who have done so within the three months before joining this trial

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Chris Gill, PhD, Ulster University, Human Intervention Studies Unit, Coleraine, Co. Londonderry, BT52 1SA, United Kingdom.

Phone: +44 28 7012 3181

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University of Ulster
Registry
ClinicalTrials.gov
Start date
25 November 2025
Est. completion
1 June 2027

Where this trial is recruiting

🇬🇧 United Kingdom

Primary endpoints

Differences in Polyphenol-derived metabolite concentrations pre, mid, & post intervention - stool; Differences in Polyphenol-derived metabolite concentrations pre, mid, & post intervention - blood; Differences in microbiome levels pre, mid, & post intervention - Stool; Differences in microbiome levels pre & post intervention - Blood; Differences in microbiome levels pre, mid, & post intervention - Stool; Differences in microbiome levels pre, mid, & post intervention - Blood; Differences in Cognitive Measures pre, mid, & post intervention - Executive Function; Differences in Cognitive Measures...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov