Phase 3 Lung Cancer Trial, Recruiting NCT07226999 Sponsor: Pfizer Condition: Lung Cancer
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Phase 3 Lung Cancer Trial, Recruiting

NCT07226999
Recruiting Phase 3 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with extensive-stage small cell lung cancer (a type of lung cancer that has spread), confirmed through a tissue or cell sample.
  • People who have not yet received chemotherapy, radiation, or combined chemo-radiation treatment for this stage of their lung cancer.
  • People who were previously treated with chemotherapy or radiation with the aim of curing an earlier, less advanced stage of this lung cancer, provided that treatment ended at least 6 months ago.
  • People who have at least one tumour that can be measured on scans, according to a standard measurement system used in cancer trials.
  • People whose overall physical health and ability to carry out daily activities falls within a certain range on a standard medical scale (confirm with trial site for specific details).
  • People whose liver, kidneys, and other organs are functioning well enough to meet the trial's requirements (confirm with trial site for specific details).

Who may not be able to join:

  • People who have active cancer spread to the brain, brainstem, the lining of the brain or spinal cord, or who have pressure on the spinal cord.
  • People who have a condition where cancer cells have spread into the fluid surrounding the brain and spinal cord.
  • People who have a significant medical risk of serious bleeding or abnormal connections forming between body tissues (fistula).
  • People who have been diagnosed with another type of cancer within the past 3 years.
  • People who have an active autoimmune disease (where the immune system attacks the body) that has required ongoing medical treatment within the past 2 years.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Pfizer CT.gov Call Center, Pfizer

Phone: 1-800-718-1021

Australian sites

Westmead Hospital, Westmead, New South Wales
Sunshine Coast University Hospital, Birtinya, Queensland

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Registry
ClinicalTrials.gov
Start date
9 December 2025
Est. completion
14 June 2030

Where this trial is recruiting

🇦🇺 Australia 🇨🇳 China 🇫🇷 France 🇩🇪 Germany 🇮🇹 Italy 🇯🇵 Japan Puerto Rico 🇪🇸 Spain 🇹🇼 Taiwan 🇺🇸 United States

2 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Phase 2: Confirmed Objective Response Rate (ORR) per Response Evaluation Criteria in Solid Tumors version 1.1 [RECIST 1.1] based on the investigator's assessment; Phase 2: Number of participants with treatment-emergent adverse events; Phase 3: Overall Survival (OS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov