Phase 2 Eczema Trial, Recruiting NCT07230860 Sponsor: Janssen Research & Development, LLC Condition: Eczema
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Phase 2 Eczema Trial, Recruiting

NCT07230860
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are generally in good health based on a physical exam, medical history, vital signs, and a heart tracing (ECG) done at the screening visit
  • You have been diagnosed with chronic atopic dermatitis (eczema) for at least 1 year before the screening visit, following recognised medical guidelines
  • Your eczema is rated as moderately severe or worse on standard medical scoring scales at both the screening visit and the start of the study
  • At least 10% of your body surface area is affected by eczema at both the screening visit and the start of the study
  • Within the past 6 months, your eczema did not respond well enough to medicated creams or ointments, or those treatments were not suitable for you — OR within the past 12 months, your eczema did not respond well enough to systemic (whole-body) treatments
  • You are willing and able to sign a consent form showing you understand the study and agree to take part
  • You are able and willing to attend scheduled visits, follow the treatment plan, have lab tests done, and follow any lifestyle guidelines required by the study
  • If you choose to take part in any optional sub-studies, you are willing to sign a separate consent form for those

Who may not be able to join:

  • You have had a problem with substance or alcohol misuse within the past year
  • Your screening tests (heart tracing, blood tests, or urine tests) show results that the study doctor considers significant enough to affect your safety or the study results
  • You have a known or suspected weakened immune system, or a history of serious infections that the body normally fights off easily
  • You have previously received the study drug JNJ-95597528
  • You have a known allergy or sensitivity to JNJ-95597528 or any of its ingredients, to any biologic medication, or to certain types of laboratory-made antibody treatments (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Janssen Research & Development, LLC Clinical Trial, Janssen Research & Development, LLC

Phone: 844-434-4210

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
20 January 2026
Est. completion
19 November 2026

Where this trial is recruiting

🇦🇷 Argentina 🇧🇷 Brazil 🇨🇦 Canada 🇨🇳 China 🇩🇪 Germany 🇯🇵 Japan 🇵🇱 Poland 🇹🇼 Taiwan 🇺🇸 United States

Primary endpoints

Proportion of Participants with Eczema Area and Severity Index (EASI) 75 Response at Week 12

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov