Phase 2 Breast Cancer Trial, Recruiting (NCT07233499)

Phase 2 Breast Cancer Trial, Recruiting NCT07233499 Sponsor: Ain Shams University Condition: Breast Cancer

Printed from Voxsanity (voxsanity.com.au) — NCT07233499 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

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Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

You are 18 years of age or older
You have been recently diagnosed with early or locally advanced HER2-positive breast cancer
Your heart is pumping at a normal level (above 50%) based on a recent test (confirm with trial site)
You are planned to receive HER2-targeted treatments either before or after surgery

Who may not be able to join:

You are older than 65 years of age
Your cancer originated somewhere other than the breast
You are currently pregnant or breastfeeding
You are currently taking certain heart-protecting medications, such as ACE inhibitors, calcium channel blockers, ARBs, or beta blockers (confirm with trial site)
You have been diagnosed with a condition where the heart muscle is weakened or damaged (either now or found at the start of the study)
You have a history of reduced blood supply to the heart, such as a heart attack or coronary artery disease
You have a medical reason why you cannot take a type of medication called beta blockers (confirm with trial site)
You have a known allergy or sensitivity to a medication called nebivolol
Your heart cannot be clearly seen on an ultrasound scan (confirm with trial site)

⚠️ Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 12 July 2026

Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.

Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 01001701461

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT07233499

Sponsor: Ain Shams University

Phase: Phase 2

Status: Recruiting

Condition: Breast Cancer

Trial contact: 01001701461

More information: https://clinicaltrials.gov/study/NCT07233499

Eligibility summary (AI generated)

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

You are 18 years of age or older
You have been recently diagnosed with early or locally advanced HER2-positive breast cancer
Your heart is pumping at a normal level (above 50%) based on a recent test (confirm with trial site)
You are planned to receive HER2-targeted treatments either before or after surgery

Who may not be able to join:

You are older than 65 years of age
Your cancer originated somewhere other than the breast
You are currently pregnant or breastfeeding
You are currently taking certain heart-protecting medications, such as ACE inhibitors, calcium channel blockers, ARBs, or beta blockers (confirm with trial site)
You have been diagnosed with a condition where the heart muscle is weakened or damaged (either now or found at the start of the study)
You have a history of reduced blood supply to the heart, such as a heart attack or coronary artery disease
You have a medical reason why you cannot take a type of medication called beta blockers (confirm with trial site)
You have a known allergy or sensitivity to a medication called nebivolol
Your heart cannot be clearly seen on an ultrasound scan (confirm with trial site)

⚠️ Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 12 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Phase 2

Sponsor

Ain Shams University

Registry

ClinicalTrials.gov

Start date

1 January 2025

Est. completion

1 February 2027

Where this trial is recruiting

🇪🇬 Egypt

Primary endpoints

Measurement of Left ventricular ejection fraction by Echocardiography

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov