Phase 1 Alzheimer's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have been diagnosed with either Alzheimer's disease dementia or mild memory and thinking problems (Mild Cognitive Impairment) that are believed to be caused by Alzheimer's disease, based on recognised medical guidelines.
- You are willing and able to take part in all parts of the study, either on your own or with the help of a study partner (such as a family member or carer).
- You can speak and understand the language used in the tests at the study location.
- You have good enough vision and hearing to complete thinking and memory tests — glasses and hearing aids are allowed.
- If you are already taking medication for Alzheimer's symptoms, you have been on a stable, unchanged dose for at least 8 weeks before joining the study.
- You agree not to take part in any other research studies while this study is ongoing.
Who may not be able to join:
- You have another medical condition (aside from Alzheimer's disease) that could affect your memory or thinking.
- A brain scan (MRI) shows abnormalities that would make a lumbar puncture (spinal fluid test) unsafe for you.
- You have other significant brain abnormalities that the study doctor considers a concern (confirm with trial site).
- You have a history of schizophrenia, schizoaffective disorder, major depression, or bipolar disorder.
- You have an unstable or poorly controlled condition affecting your heart, lungs, liver, kidneys, digestive system, hormones, or blood that could affect your safety or interfere with the study results.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Clinical Trials, Hoffmann-La Roche
Phone: 888-662-6728 (U.S. and Canada)
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Percentage of Participants with Adverse Events; Change From Baseline in Columbia-Suicide Severity Rating Scale (C-SSRS) Scores
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.