Phase 1 Eczema Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

Part A (Healthy Volunteers):

• People who are healthy male or female volunteers between 18 and 65 years old
• People whose body weight falls within a moderate range (BMI of 18.5 to less than 32.5)
• Women who could become pregnant must have a negative pregnancy test

Part B (Atopic Dermatitis Patients):

• People between 18 and 65 years old
• People whose body weight falls within a moderate range (BMI of 18.5 to less than 40.0)
• People who have been diagnosed with atopic dermatitis (eczema) for at least 12 months before the study start date
• People with moderate-to-severe atopic dermatitis, measured by specific scoring tools used by doctors at screening (confirm with trial site)
• People whose eczema covers 10% or more of their body surface area
• People who have not responded well enough to creams, ointments, or other skin-applied treatments in the past
• People who have been experiencing significant itching (a score of 4 or more out of 10 on average) in the 7 days before being enrolled
• Women who could become pregnant must have a negative pregnancy test

Who may not be able to join:

Parts A and B:

• People who test positive for HIV, hepatitis B, hepatitis C, or active tuberculosis, or who have immune system disorders or autoimmune diseases
• People with a significant history of metabolic, liver, kidney, or blood disorders
• People with abnormal heart rhythm or electrical activity findings on a heart tracing (ECG)
• People with abnormal blood test results, including low blood cell counts or signs of liver or kidney problems
• People with a history of drug abuse or addiction in the 6 months before screening
• People who currently smoke or have used any tobacco or nicotine products in the 6 months before dosing
• People who have donated more than 500mL of blood within 2 months of the dosing date

Part B only:

• People who have other skin conditions that could make it difficult to assess atopic dermatitis accurately
• People with an uncontrolled long-term illness that may require courses of oral steroid tablets
• People whom the trial investigator determines should not participate for medical, psychiatric, or social reasons (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.