Phase 1 study for people with Eczema
Recruiting Phase 1
This trial at a glance
Where this trial is running
| Site | City | State or country | Status at this site |
|---|---|---|---|
| Veracity Clinical Research | Woolloongabba | QLD | Recruiting |
| Skin Health Institute | Carlton | VIC | Recruiting |
voxsanity.com.au · trial sites from public registries · registry record synced 11 October 2026 · not medical advice
Who can join
The official eligibility criteria
Registry text, reproduced exactly. These are the words the trial's sponsor published on ClinicalTrials.gov. They have not been edited, shortened or rewritten, and they are written for researchers rather than for patients.
Inclusion Criteria:
* Part A:
1. Healthy male and female volunteers, 18-65 years of age
2. Body mass index (BMI) between ≥ 18.5 and \< 32.5 kg/m2
3. Negative pregnancy tests for women of childbearing potential.
* Part B:
1. 18-65 years of age;
2. BMI between ≥18.5 and \<40.0 kg/m2
3. Have a diagnosis of AD at least 12 months prior to Day 1;
4. Moderate-to-severe AD at Screening and Baseline visit, defined as:
1. Eczema Area and Severity Index (EASI) score ≥ 16;
2. Affected Body Surface Area (BSA)≥ 10%;
3. vIGA-AD™ score ≥ 3
5. History of an inadequate response to treatment with topical medications
6. Average peak pruritus numeric rating scale (PP-NRS) score ≥4 in the 7 days before randomization.
7. Negative pregnancy tests for women of childbearing potential.
Exclusion Criteria:
* Part A and B:
1. Significant health issues, such as positive tests for human immunodeficiency virus (HIV), hepatitis C virus (HCV), hepatitis B surface antigen (HBsAg), active tuberculosis, immunodeficiencies or autoimmune diseases.
2. History of major metabolic, liver, kidney, hematologic or other significant disorders.
3. Abnormal Electrocardiogram (ECG) findings
4. Clinically relevant abnormal lab results, including low blood counts, or abnormal liver and kidney function.
5. History of drug abuse or addiction within 6 months prior to screening
6. Current smoker or use of any nicotine or tobacco containing products within the last 6 months prior to dosing.
7. Donated \>500mL blood within 2 months of dosing.
* For Part B only:
1. Presence of dermatologic conditions and/or comorbidities that might confound the diagnosis of AD and/or might interfere with study assessments.
2. Uncontrolled chronic disease that might require bursts of oral corticosteroids.
3. Any other sound medical, psychiatric, and/or social reason as determined by the investigator.
Dates on the record
Results, publications and the official record
- No results are posted on the official record yet.
- No publications are listed on the official record yet.
- Official record and contacts on ClinicalTrials.gov – contact details for each site are kept there, and are not copied onto this page.
Sources and dates
- ClinicalTrials.gov – the record this page reformats
- ClinicalTrials.gov processing date: 7 August 2026.
- This page last checked by Voxsanity: 11 October 2026.
Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.
Not medical advice.
Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.
Letter for your doctor
A one-page summary of this trial to print or email to your GP. It carries the registry's own record of the trial and its eligibility criteria, and nothing Voxsanity has written about whether it suits you.