Crohn's Disease and Colitis Trial, Recruiting NCT07242248 Sponsor: Janssen-Cilag Ltd. Condition: Crohn's Disease and Colitis
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Crohn's Disease and Colitis Trial, Recruiting

NCT07242248
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Your doctor has decided to prescribe you a medication called guselkumab (a biologic treatment) for your condition, and you are about to start it or have just been enrolled before your first dose
  • You have an official diagnosis of moderate-to-severe Crohn's Disease or Ulcerative Colitis documented in your medical records
  • You are willing and able to sign a consent form allowing the trial team to check your medical records as required

Who may not be able to join:

  • You have a medical reason why guselkumab is not safe for you to take (confirm with trial site)
  • You are currently taking part in another clinical trial that involves a treatment or intervention
  • You have previously been treated with certain medications that target a protein called IL-23, specifically guselkumab (Tremfya®), risankizumab (Skyrizi®), or mirikizumab (Omvoh®) — however, if you have previously taken a drug called ustekinumab, you may still be eligible
  • You have already been treated with more than 4 different advanced therapies (such as biologics or certain tablets) for your bowel condition
  • You are not able to give your own informed consent to take part in the trial

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Janssen-Cilag Limited Clinical Trial, Janssen-Cilag Limited

Phone: 844-434-4210

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Janssen-Cilag Ltd.
Registry
ClinicalTrials.gov
Start date
17 November 2025
Est. completion
5 March 2029

Where this trial is recruiting

🇬🇧 United Kingdom

Primary endpoints

Number of Participants Achieving Clinical Remission for Crohn's Disease (CD) as Measured by Harvey-Bradshaw Index (HBI); Number of Participants Achieving Clinical Remission for Ulcerative Colitis (UC) as Measured by Partial Mayo Score (PMS); Number of Participants Achieving Clinical Response for CD as Measured by HBI; Number of Participants Achieving Clinical Response for UC as Measured by PMS; Number of Participants Achieving Corticosteroid-free Remission for CD as Measured by HBI; Number of Participants Achieving Corticosteroid-free Remission for UC as Measured by PMS; Number of Participants...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov