Phase 4 Prostate Cancer Trial, Recruiting NCT07252726 Sponsor: Ottawa Hospital Research Institute Condition: Prostate Cancer
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Phase 4 Prostate Cancer Trial, Recruiting

NCT07252726
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Breast Cancer Group (Cohort A):

  • People who have breast cancer that has spread to other parts of the body, and whose cancer is driven by hormones (hormone receptor positive)
  • People whose doctor plans to treat them with hormone therapy and a specific type of targeted therapy called a CDK4/6 inhibitor — either Ribociclib or Palbociclib — as their first treatment for the cancer that has spread
  • People aged 18 or older
  • People who are able to give consent by speaking (rather than in writing)
  • People who are willing and able to fill in questionnaires as required by the study

Prostate Cancer Group (Cohort B):

  • People who have prostate cancer that has spread to other parts of the body and is still responding to hormone-lowering treatment
  • People whose doctor plans to treat them with a hormone-blocking medication (either enzalutamide, apalutamide, or abiraterone acetate) alongside treatment to reduce testosterone levels
  • People aged 18 or older
  • People who are able to give consent by speaking (rather than in writing)
  • People who are willing and able to fill in questionnaires as required by the study

Who may not be able to join:

Breast Cancer Group (Cohort A):

  • People for whom there is a medical reason that prevents their hormone therapy or CDK4/6 inhibitor being taken in the morning or evening
  • People whose doctor plans to use a CDK4/6 inhibitor called abemaciclib, as this medication needs to be taken twice a day

Prostate Cancer Group (Cohort B):

  • People for whom there is a medical reason that prevents their hormone-blocking medication being taken in the morning or evening
  • People whose doctor plans to use a medication called darolutamide, as this requires twice-daily dosing
  • People whose treatment plan includes a chemotherapy called docetaxel alongside their hormone-blocking medication

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 12 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Principal Investigator: Marie-France Savard, MD, The Ottawa Hospital

Phone: 613-737-7700

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Sponsor
Ottawa Hospital Research Institute
Registry
ClinicalTrials.gov
Start date
2 February 2026
Est. completion
1 March 2027

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Feasibility: accrual per site; Feasibility: participation rate; Feasibility: number of participants who received allocated intervention

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov