Early Phase 1 Peripheral Arterial Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have at least 3 toes on each foot
- People whose feet are otherwise in generally intact condition
- People who do not have skin conditions such as eczema, thickened skin, hardened skin disorders, or excessive sweating on the areas of the foot where the study product would be applied
- People who agree to apply the study product to painful areas of the feet as directed by research staff
- People who agree to apply the study product to their feet twice per day as instructed
- People who agree to wait 60 minutes after each application before completing pain rating forms
- People who agree to wait at least 60 minutes before washing their feet after applying the study product, unless a burning sensation occurs shortly after application
- People who are willing to use the study product without knowing which specific version they have been given
Who may not be able to join:
- People younger than 25 or older than 75 years of age
- People with any skin condition that could affect the skin's surface or change sensation in the feet
- People who have had open wounds, skin sores, infections, skin irritation (such as poison oak), eczema, injury, or burns (including sunburn) on the feet within the past 30 days
- People who have recently had surgery involving the feet
- People who are currently using topical products on their feet — including herbal, cannabinoid, medicated patches, pain relief creams or gels, anti-inflammatory products, or steroid products — unless those products have been used consistently and regularly before the study began
- People who currently misuse substances
- People with a known allergy or sensitivity to chili peppers, coconut oil, shea butter, or sunflower seed oil
- People who are receiving other foot pain treatments at the same time, such as massage, electrophoresis, or red light therapy (note: mobility-related therapies such as physical therapy or exercise may be acceptable — confirm with trial site)
- People who are currently enrolled in another clinical trial
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Robert Carpenter, MD, Carilion Clinic
Phone: (540) 240-1695
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Significant reduction in foot pain in participants with chronic diabetic neuropathic foot pain.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.