Breast Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Women aged 70 or older who have been diagnosed with invasive breast cancer and have not yet had surgery, drug treatments, or radiation therapy for this diagnosis (note: people whose invasive cancer was found after a biopsy done for an unrelated abnormality may also be included)
• The breast cancer must have been found through a routine mammogram screening
• The tumor must be 2cm or smaller, with no sign that cancer has spread to the lymph nodes, based on ultrasound or mammogram measurements — with specific grade requirements depending on size: tumors up to 1cm may be Grade I or Grade II; tumors between 1cm and 2cm must be Grade I only (confirm with trial site if unsure of your grade or size)
• The breast cancer must test positive for estrogen receptors (ER+) and negative for the HER2 protein (HER2−), as confirmed by a local pathology laboratory using specific testing thresholds
• People with cognitive impairment may be eligible, provided a legally authorised representative is able to sign the consent forms on their behalf
• Stored tissue samples from a previous biopsy must be available and confirmed before registration

Who may not be able to join:

• People who have already received any anti-cancer treatment — such as hormone therapy, chemotherapy, radiation, or an experimental therapy — for their current breast cancer diagnosis
• People whose current breast cancer is considered by their treating doctor to be a recurrence of a previous cancer
• People whose cancer is found in more than one area of the breast (multifocal or multicentric disease)
• People with a history of a non-invasive cancer called DCIS in the other breast, or LCIS in either breast, or who have previously had radiation to the affected breast
• People diagnosed with inflammatory breast cancer
• Men with breast cancer
• People with serious, uncontrolled medical conditions that their treating doctor believes would create unacceptable safety risks — this includes severe digestive or bowel conditions that affect the absorption of oral medications (such as uncontrolled Crohn's disease, ulcerative colitis, or chronic nausea, vomiting, or diarrhoea), or severe liver disease (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.