Phase 2 Oesophageal Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults aged 18 or older, of any gender
• People who have been diagnosed with a specific type of oesophageal cancer (squamous cell cancer in the chest area of the oesophagus), confirmed by tissue testing, at a particular stage of disease (confirm with trial site for stage details)
• People who had surgery to fully remove the cancer (known as R0 resection) between 4 and 16 weeks before joining the trial
• People with a good general level of physical functioning, rated 0 or 1 on a standard medical scale (meaning able to carry out normal daily activities with little or no restriction)
• People whose doctors expect them to survive at least 12 months
• People whose heart is pumping blood effectively (a specific heart function measure above 50%)
• People whose blood counts, liver function, and kidney function are within acceptable ranges as determined by standard blood tests

Who may not be able to join:

• People whose cancer was initially considered inoperable and who received treatment to try to make it operable before surgery
• People who experienced serious complications after surgery that make further treatment unsuitable
• People who have already received any additional cancer treatment after surgery
• People who are currently receiving or have previously received chemotherapy, radiotherapy, or targeted therapy for this cancer
• People with a history of another cancer, unless that cancer has been in full remission for at least 5 years and no further treatment for it is expected during the study
• People with active autoimmune conditions (where the immune system attacks the body), such as certain lung, gut, liver, or kidney conditions — some exceptions may apply (confirm with trial site)
• People with an active hepatitis B or hepatitis C infection
• Women who are pregnant or breastfeeding, or women of childbearing age who are not using contraception during the trial; also people with immune system deficiencies, HIV, a history of organ transplant, or bone marrow transplant
• People with serious heart conditions that are not well controlled, such as significant heart failure, unstable chest pain, a heart attack within the past 6 months, or certain uncontrolled heart rhythm problems
• People considered unsuitable by the trial investigators after an overall assessment

Important: Always verify eligibility with the trial site directly before applying.