Motor Neurone Disease Trial, Recruiting NCT07268833 Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta Condition: Motor Neurone Disease
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Motor Neurone Disease Trial, Recruiting

NCT07268833
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

People with ALS (Lou Gehrig's disease):

  • You are 18 years of age or older
  • You have been formally diagnosed with ALS using standard diagnostic guidelines
  • Your symptoms started less than 24 months (2 years) ago

People who carry a gene linked to ALS but have no symptoms yet:

  • You are 18 years of age or older
  • You have a genetic variation known to increase the risk of ALS, and at least one close family member has been diagnosed with ALS

Healthy volunteers (control group):

  • You are 18 years of age or older
  • You have not been diagnosed with any brain/nerve degenerative disease or neuromuscular condition

People with other brain/nerve degenerative diseases (such as Alzheimer's, Parkinson's, FTD, or DLB):

  • You are 18 years of age or older
  • You have a formal diagnosis of one of these conditions made using recognised medical guidelines

People with neuromuscular diseases:

  • You are 18 years of age or older
  • You have been diagnosed with a nerve condition affecting how signals travel through your nerves (confirm with trial site)

Who may not be able to join:

  • People with ALS whose lung function has dropped significantly (below 60% of normal breathing capacity)
  • People with ALS who are experiencing serious problems with nutrition or breathing
  • Anyone — in any group — who has significant liver disease or long-term kidney disease
  • Anyone — in any group — who has an active infection or a metabolic condition that could affect certain biological markers being measured in this study (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Registry
ClinicalTrials.gov
Start date
24 October 2024
Est. completion
1 April 2027

Where this trial is recruiting

🇮🇹 Italy

Primary endpoints

Diagnostic ALS biomarkers

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov