Phase 2 Macular Degeneration Trial, Recruiting NCT07275840 Sponsor: Innovent Biologics Technology Limited (Shanghai R&D Center) Condition: Macular Degeneration
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Phase 2 Macular Degeneration Trial, Recruiting

NCT07275840
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have signed a consent form before taking part in the research
  • Men or women aged 50 or older at the time of signing the consent form
  • People who have abnormal blood vessel growth (called CNV) under or involving the central area of the retina (the macula), caused by a condition known as wet age-related macular degeneration (wet AMD)
  • People whose vision in the study eye falls within a specific range on a standardised eye chart test (between 19 and 78 ETDRS letters, inclusive) at the start of the trial

Who may not be able to join:

  • People whose study eye has other eye conditions or health conditions that, in the investigator's judgement, could interfere with treatment results or make the results difficult to interpret
  • People whose study eye has glaucoma that cannot be controlled
  • People who have an active infection or inflammation in or around either eye
  • People whose non-study eye has severe vision loss
  • People whose study eye received an anti-VEGF injection (a type of eye treatment) within 90 days before the start of the trial
  • People whose study eye received an anti-complement treatment within 90 days before the start of the trial
  • People whose study eye has ever received the specific study drug (IBI302) at any point before the trial
  • People with high blood pressure that cannot be controlled
  • People whose blood sugar control measure (HbA1c) was above 10.0% within 28 days before the screening visit
  • People who meet any other exclusion criteria set out in the trial protocol (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 86 15821084695

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Innovent Biologics Technology Limited (Shanghai R&D Center)
Registry
ClinicalTrials.gov
Start date
5 December 2025
Est. completion
30 August 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Proportion of participants whose best corrected visual acuity (BCVA) of the study eye decreased by less than 15 letters from baseline as measured by the visual acuity chart in the early treatment diabetic retinopathy study (ETDRS) at week 52

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov