Chronic Fatigue Syndrome Trial, Recruiting NCT07278388 Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc. Condition: Chronic Fatigue Syndrome
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Chronic Fatigue Syndrome Trial, Recruiting

NCT07278388
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 18 and 75 years old.
  • You have been officially diagnosed with Long COVID (also called post-acute sequelae of SARS-CoV-2 or PASC), confirmed using a specific symptom scoring system where a score above 12 qualifies (confirm with trial site).
  • You are currently experiencing fatigue and/or brain fog, as measured by specific symptom questionnaires used by the trial team.

Who may not be able to join:

  • You have a neurological condition such as stroke, head injury, epilepsy, seizures, brain tumors, brain surgery, Parkinson's Disease, or any other nerve or muscle disease.
  • You have been diagnosed with a serious mental health condition such as severe depression or schizophrenia.
  • You have congestive heart failure (a condition where the heart does not pump blood effectively).
  • You have a circulation problem in your legs that causes pain when walking (peripheral artery disease with claudication).
  • You have or have had cancer.
  • You have lung or kidney failure.
  • You have unstable chest pain (unstable angina).
  • Your blood pressure is very high and not controlled (above 190/110).
  • You have severe difficulty speaking or understanding language (severe aphasia).
  • You have bone, joint, or chronic pain conditions.
  • You have metal in your body or metal implants, due to safety risks from the magnetic equipment used in the study.
  • You are on immune-related medication that you have been taking for less than 6 months before the study begins.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Vikram Chib, PhD, Johns Hopkins University; Kennedy Krieger Institute

Phone: 443-923-2716

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Registry
ClinicalTrials.gov
Start date
16 July 2025
Est. completion
31 December 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Comparison between PASC and HC - difference in mean Assessment Error; Comparing between PASC and HC - difference in BBB permeability; Comparing between PASC and HC - Regions of the brain that are sensitive to Assessment error as a function of disease state; The modulatory effect of BBB permeability on the relationship between Neural Activity and Effort Assessment; Comparing between PASC and HC - Difference in momentary subjective fatigue ratings; Comparing between PASC and HC - Difference in Mean Acceptance Rate of Risky Effort Options between rested/baseline and fatigue choices; Comparing bet...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov