Phase 3 Polymyalgia Rheumatica Trial, Recruiting NCT07279688 Sponsor: University Hospital, Brest Condition: Polymyalgia Rheumatica
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Phase 3 Polymyalgia Rheumatica Trial, Recruiting

NCT07279688
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are at least 50 years old.
  • You have been diagnosed with a condition called Polymyalgia Rheumatica (PMR), either newly diagnosed or in a form that has not responded well to previous treatment.
  • You are either not taking steroid medications (corticosteroids), or you are taking a low dose (less than 15 mg per day), and this has been the case for at least 15 days before joining the trial.
  • Your PMR activity score (a measure of how active your condition is) is above a certain level, indicating your condition is currently active (confirm with trial site).
  • You do not have other inflammatory joint, tissue, or blood vessel diseases.
  • You are able to understand and sign a consent form agreeing to take part.
  • You are covered by French health insurance.

Who may not be able to join:

  • You have signs of a related condition called giant cell arteritis (a type of blood vessel inflammation).
  • You have high blood pressure or heart/cardiovascular disease that is not well controlled.
  • You have had a blood clot in a vein (such as a deep vein thrombosis or a clot in the lungs) in the past 12 weeks, or you have had more than one such event in the past.
  • You have another serious unstable or uncontrolled illness that is not related to PMR.
  • You are planning to have major surgery during the study, or you have certain medical conditions, blood test abnormalities, or other health concerns that would make joining unsafe (confirm with trial site).
  • You are a current smoker and are over 65 years old.
  • You currently have an active infection that is not under control.
  • You are currently taking a medication called probenecid.
  • Certain liver-related blood test results are too high (confirm with trial site).
  • Your white blood cell counts (specifically neutrophils and lymphocytes) are too low, which could affect your immune system.
  • You are under legal protection or guardianship (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: +33298223333

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
University Hospital, Brest
Registry
ClinicalTrials.gov
Start date
18 December 2025
Est. completion
1 November 2028

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Following of the Polymyalgia Rheumatica Activity score

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov