Phase 2 Alzheimer's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed with Alzheimer's disease, or a combination of Alzheimer's disease and vascular disease (a type of dementia related to blood flow in the brain)
- People whose score on a standard memory and thinking test (called the MMSE) falls between 10 and 28 out of 30
- People who have been assessed as having a significant level of apathy (a persistent lack of motivation or interest)
- People who have been on a stable, unchanged dose of any psychiatric or mood-related medications
- People who have a care partner (such as a family member or carer) who spends at least 10 hours per week with them
Who may not be able to join:
- People who are currently experiencing a major depressive episode
- People who are currently experiencing significant agitation, delusions (false beliefs), or hallucinations (seeing or hearing things that are not there)
- People who are currently taking a medication that affects dopamine in the brain, other than methylphenidate
- People who do not pass a standard safety checklist for a brain stimulation procedure called TMS — for example, those with certain pacemakers, metallic implants in or near the head, or a history of epilepsy
- People who have a significant brain or nervous system condition beyond Alzheimer's disease, or who have a history of seizures, as determined by the study doctor
- People who have any other health condition that the study doctor considers makes it medically unsafe to participate
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in Neuropsychiatric Inventory-Apathy (NPI-A) score
Can't join this trial?
Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.