Phase 3 Stroke Trial, Recruiting NCT07282041 Sponsor: National University of Singapore Condition: Stroke
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Phase 3 Stroke Trial, Recruiting

NCT07282041
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults between 21 and 80 years of age
  • People who are able to give their own consent to participate
  • People who score 3 or lower on a disability scale called the Modified Rankin Score, which measures how much a stroke or similar condition affects daily life (confirm with trial site)
  • People who have had a TIA (sometimes called a "mini-stroke") or a mild stroke in the past 3 months, and who also have a significant narrowing of certain blood vessels in the brain along with reduced blood flow regulation in the brain (confirm with trial site)

Who may not be able to join:

  • People with very severe kidney disease (stage 5) or who are currently on dialysis
  • People who have been diagnosed with cancer within the past 3 years
  • People who are already being planned for a procedure to open or bypass blocked arteries in the heart or neck
  • People who have a history of inflammation of the pancreas (pancreatitis)
  • People who have a history of a specific type of thyroid cancer called medullary thyroid cancer
  • People who have a heart rhythm condition called atrial fibrillation
  • People who have any other condition that the trial doctor believes would make it difficult to follow the trial requirements
  • People with diabetes who are currently taking certain diabetes medications (called SGLT2 inhibitors or pioglitazone), unless those medications can be safely stopped — and people on another diabetes medication called a DPP-IV inhibitor who are placed in the treatment group would need to stop that medication during the trial (confirm with trial site regarding your specific medications)
  • People who have a known allergy to a medication called Acetazolamide
  • Women who are pregnant or breastfeeding

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: vijay K sharma, MD, National University of Singapore

Phone: 91389555

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
National University of Singapore
Registry
ClinicalTrials.gov
Start date
17 December 2025
Est. completion
1 December 2030

Where this trial is recruiting

🇸🇬 Singapore

Primary endpoints

To evaluate whether GLP1 RA (Dulaglutide) therapy would improveme cerebral vasodilatory reserve by at least 4 points in patients with severe stenosis of ICA or MCA

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov