Phase 4 Polymyalgia Rheumatica Trial, Recruiting NCT07286214 Sponsor: Sanofi Condition: Polymyalgia Rheumatica
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Phase 4 Polymyalgia Rheumatica Trial, Recruiting

NCT07286214
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 50 or older who have been diagnosed with a condition called polymyalgia rheumatica (PMR), based on recognised medical guidelines
  • People who are either newly diagnosed with PMR (and have taken steroid tablets for no more than 6 weeks), or who have had an early return of PMR symptoms within the past 12 weeks while already on a low dose of steroids
  • People who are willing and able to take a steroid tablet called prednisone at a dose of 15 mg per day at the start of the trial
  • People who are willing to use contraception in line with local guidelines for clinical trial participants (applies to both men and women)

Who may not be able to join:

  • People who have been diagnosed with a related condition called Giant Cell Arteritis (GCA)
  • People who also have rheumatoid arthritis, another type of inflammatory joint condition, a connective tissue disease, or fibromyalgia
  • People who have an underactive thyroid that is not being adequately treated
  • People with a current or recurring serious infection, including tuberculosis (TB), hepatitis B or C, HIV, or shingles (herpes zoster) (confirm with trial site)
  • People with poorly controlled diabetes (confirmed by a specific blood test result)
  • People currently taking immune-suppressing medications, including steroid tablets (confirm with trial site)
  • People who have or have had cancer
  • People who have received an organ transplant

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Phone: 800-633-1610

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Sponsor
Registry
ClinicalTrials.gov
Start date
12 May 2026
Est. completion
4 June 2029

Where this trial is recruiting

🇨🇦 Canada 🇺🇸 United States

Primary endpoints

Sustained remission at Week 52 (yes/no) in participants with early relapsing polymyalgia rheumatica (PMR) who received sarilumab 200 mg q2w with 52-week prednisone taper

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov