Phase 1 COPD Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 18 to 65 years (for the healthy volunteer part) or 35 to 75 years (for the patient part), with a body weight no higher than 120 kg and a body mass index between 18 and 32
- Women of childbearing potential who have a negative pregnancy test result
- People who do not drink alcohol in the 24 hours before each study visit
- People who are non-smokers, ex-smokers, or current smokers who smoke no more than 5 cigarettes per day
- People who use adequate contraception, if they are men or women who could potentially have children
- People with no significant medical conditions or serious medical history
- For the patient part only: people who have a confirmed diagnosis of COPD, with specific lung function test results showing an FEV1/FVC ratio below 0.70 after using a bronchodilator, and an FEV1 result between 50% and 80% of the expected value (confirm with trial site)
Who may not be able to join:
- People who test positive for HIV, hepatitis B, or hepatitis C
- People who have immune system disorders, autoimmune diseases, cancer, or a history of conditions that increase the risk of infections
- People with a history of major problems affecting metabolism, skin, liver, kidneys, blood, or other serious health conditions
- People with significantly abnormal blood test results, including problems with blood cell counts, liver enzyme levels, or kidney function
- People who test positive for drugs or alcohol, or who have abnormal vital signs, at the screening visit or the day before the study begins
- People with abnormal heart trace (ECG) results
- People with a history of drug or alcohol misuse in the past two years
- People with a history of severe allergic reactions or serious sensitivity to medications
- For the patient part only: people who currently have another significant lung disease
- For the patient part only: people who have serious or unstable heart or cardiovascular conditions
- For the patient part only: people who have had a significant infection recently
- For the patient part only: people who are unable to perform breathing tests (spirometry)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: +86 18001322760
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Number of participants with adverse events following single and multiple administration of BBT002; Number of participants with change in Laboratory assessments; Number of participants with change in vital sign measurements following dose administration.; Number of participants with change in physical examination following dose administration.; Number of participants with change in 12-lead ECG readings
Can't join this trial?
Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.