Osteoarthritis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 65 years or older
- People who are scheduled for a planned (non-emergency) knee replacement surgery on one knee, under spinal or general anaesthesia
- People whose overall health status falls within a range that anaesthetists classify as ASA I, II, or III (meaning from generally healthy to having some controlled medical conditions) (confirm with trial site)
- People for whom the surgical team plans to use a specific type of nerve-blocking pain relief called an adductor canal block as part of their pain management plan
- People who are able to describe their pain level using a numbered rating scale (for example, rating pain from 0 to 10)
- People who have given written agreement to take part in the trial
Who may not be able to join:
- People who are unwilling or unable to give formal written consent to participate
- People who have a known allergy, intolerance, or medical reason to avoid local anaesthetic medicines, specifically ropivacaine
- People who already have a significant nerve problem or nerve damage in the leg being operated on
- People who have blood clotting problems, or who are on blood-thinning medications that cannot be safely paused and that would make nerve block injections unsafe (confirm specific thresholds with trial site)
- People who have a skin infection at or near the area where the needle injection would be placed
- People with severely reduced liver or kidney function
- People who have been taking opioid pain medicines (such as strong prescription painkillers) every day for more than 30 days before surgery
- People whose thinking or memory is significantly affected in a way that would prevent them from reliably reporting their pain level, including those experiencing delirium
- People with a BMI over 40 kg/m² (confirm with trial site, as this criterion may apply)
- People who have previously had a knee replacement on the same knee, or who are having a revision (repeat) knee replacement surgery (confirm with trial site, as this criterion may apply)
- People who are pregnant or breastfeeding
- People who have taken part in another interventional clinical trial within the past 30 days
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Malgorzata Reysner, MD PhD, Poznan University of Medical Sciences
Phone: +48618738313
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Time to First Rescue Analgesia
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.