Schizophrenia Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are able to give written consent to participate.
• People who have been diagnosed with a schizophrenia-spectrum disorder and who score above 10 on a test used to assess their ability to understand and consent to research.
• People who are currently receiving care from a licensed primary care or mental health provider, such as a psychiatrist, psychologist, nurse practitioner, or licensed clinical social worker.
• People whose negative symptoms (such as reduced motivation or emotional expression) score 20 or above on a recognised clinical rating scale called the BNSS.
• People who agree to give written permission for the research team to communicate with any health care provider who has treated them in the two years before joining the study.

Who may not be able to join:

• People who have a close blood relative with inherited epilepsy or seizures, or who answer "yes" to certain questions on an epilepsy screening questionnaire.
• People taking more than 400 mg of clozapine per day who are not also taking a sufficient dose of anti-seizure medication.
• People who do not pass a safety screening questionnaire specific to TMS (a type of brain stimulation used in the trial).
• People with significant recent alcohol or other drug dependence, or whose urine test shows substances not prescribed to them (nicotine and marijuana are noted separately in the criteria — confirm details with trial site).
• People with major medical conditions that may affect normal brain function, such as stroke, brain infection, or brain tumour.
• People with certain medical devices or metal objects in or near the head, such as pacemakers, aneurysm clips, cochlear implants, stimulators, implanted pumps, or intracardiac lines, or who have unstable heart disease.
• People with a history of head injury involving loss of consciousness lasting more than 10 minutes, or a history of brain surgery.
• People who are unable to avoid alcohol or marijuana for 24 hours or more before study sessions.
• Women who are pregnant, may be pregnant, or who have had unprotected sexual intercourse without birth control in the last four weeks.
• People assessed as being at moderate-to-high risk of suicide based on a clinical rating scale (the C-SSRS), or in the judgement of the study psychiatrist or investigator.
• People with a personal or family history of deep vein thrombosis (blood clots in the veins).

Important: Always verify eligibility with the trial site directly before applying.