Asthma Trial, Recruiting NCT07292805 Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Condition: Asthma
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Asthma Trial, Recruiting

NCT07292805
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are over 18 years old
  • People who have severe asthma that is not well controlled (based on a specific asthma control score called the ACQ being above 1.5), even after trying the highest recommended level of asthma treatment
  • People who have already tried at least one biologic medicine (a type of specialist asthma injection), or for whom biologic treatment is not considered suitable by their doctor
  • People who have had 2 or more serious asthma attacks in the past year that required a course of steroid tablets, or a significant increase in their regular steroid tablet dose, for at least 3 days in a row
  • People whose lungs can still breathe out at least 50% of the expected amount of air after taking a reliever inhaler (confirm with trial site)

Who may not be able to join:

  • People who take steroid tablets every day at a dose higher than 20 mg of prednisone (or equivalent)
  • People who have been admitted to an intensive care unit and needed a breathing machine or breathing tube inserted for asthma in the past year
  • People who take blood-thinning medication that cannot be safely paused temporarily
  • People who are pregnant
  • People with a body mass index (BMI) of 35 or higher
  • People who currently smoke or have smoked heavily in the past (more than 20 pack years, which means roughly a pack a day for 20 years or equivalent)
  • People whose lungs show a reduced ability to transfer oxygen into the blood, below a certain threshold on a breathing test (confirm with trial site)
  • People who have a known allergy or sensitivity to any medicines used during a bronchoscopy (a procedure where a camera is passed into the airways)
  • People who take immune-suppressing medicines other than steroid tablets, if those medicines could affect the procedure being studied
  • People who have a bleeding disorder, problems with platelets (the blood cells that help clotting), or a low platelet count
  • People who have other serious health conditions that make the procedure being studied unsafe, such as severe heart failure, bronchiectasis, scarring lung disease, emphysema, cystic fibrosis, a blocked upper airway, or certain rare lung conditions including Churg-Strauss syndrome and allergic bronchopulmonary aspergillosis (ABPA)
  • People who have an internal or external pacemaker or a heart defibrillator device

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +31 (0)20-7329509

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Registry
ClinicalTrials.gov
Start date
9 April 2024
Est. completion
30 April 2029

Where this trial is recruiting

🇳🇱 Netherlands

Primary endpoints

Exacerbation

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov