Osteoarthritis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are 65 years of age or older
• People with a body weight that falls within a moderate, healthy range (a BMI between 18 and 30)
• People whose overall physical health before surgery is rated as good to moderately managed (ASA classification I–III — confirm with trial site if unsure which category applies)
• People who are already scheduled for a planned, non-emergency bone or joint surgery on a limb, to be performed under general anaesthesia
• People whose surgery is expected to last longer than 30 minutes
• People who are willing to take part and are able to sign a written consent form

Who may not be able to join:

• People with a known allergy to ciprofol or similar medications, or any medical reason they cannot receive these medications
• People who have signs of memory or thinking difficulties before surgery
• People with a history of serious stroke or other significant blood vessel problems in the brain
• People with a history of nerve, muscle, or psychiatric conditions
• People with a history of regularly using sedative or calming medications
• People with a history of alcohol misuse or drug use disorder
• People with a slow heart rate (fewer than 60 beats per minute)
• People with low blood pressure (mean arterial pressure below 55 mmHg)
• People with a specific irregularity in heart rhythm known as QT interval prolongation (confirm with trial site)
• People who are unable to cooperate or communicate effectively

Important: Always verify eligibility with the trial site directly before applying.