Phase 2 Psoriasis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 75 years old at the time of screening, of any gender
• People who have been diagnosed with Generalized Pustular Psoriasis (GPP) based on specific criteria set by a 2017 international medical expert group (ERASPEN)
• People who are currently experiencing an acute (sudden/active) flare-up of GPP
• People who are able to read, understand, and are willing to sign a consent form agreeing to take part
• People who are willing to attend all required study visits and follow study procedures
• Women who are able to become pregnant must agree to use contraception throughout the study and for 6 months after the study ends

Who may not be able to join:

• People whose pustules (pus-filled skin spots) appear only on raised psoriasis plaques, rather than as the generalised (widespread) GPP pattern
• People who have another skin condition or other medical condition that might make it difficult for the study doctor to assess how well the treatment is working
• People who have a severe, worsening, or uncontrolled medical condition that the study doctor considers unsuitable for participation
• People who have abnormal blood test results for certain viruses during the screening period
• People whose chest X-ray shows active tuberculosis (TB), who have had close contact with someone with active TB in the past 6 months, or who test positive on a specific TB blood test (IGRA)
• People who were hospitalised due to a serious infection in the 2 months before the study start
• People who, in the study doctor's assessment, needed antibiotics, antifungal, or antiviral medicines taken throughout the body (not just on the skin) within 2 weeks before the study start
• People who have had a rare or unusual ("opportunistic") infection in the 6 months before the study start
• People who received a live or weakened live vaccine within 12 weeks before the study start
• People who had a major surgical procedure within 4 weeks before the study start, or who have a major surgery planned during the study period
• People who received a blood transfusion within 4 weeks before the study start
• People who took part in another clinical trial of a drug or medical device within 4 weeks before the study start
• People who have a known or suspected condition — present from birth or developed later — that weakens the immune system
• People who have any currently active cancer, or who have a history of cancer of any type
• People with alcohol dependence, drug dependence, or known dependence on any specific medicine
• Women who are pregnant or currently breastfeeding
• People who are unable to tolerate receiving medicine through an intravenous (IV) drip into a vein

Important: Always verify eligibility with the trial site directly before applying.