Phase 2 Ovarian Cancer Trial, Recruiting NCT07322094 Sponsor: TORL Biotherapeutics, LLC Condition: Ovarian Cancer
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Phase 2 Ovarian Cancer Trial, Recruiting

NCT07322094
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People whose overall health and ability to carry out daily activities meets a certain minimum level (measured using a standard scale called the ECOG scale, with a score of 0, 1, or 2)
  • People who have been confirmed through laboratory testing to have a specific type of ovarian cancer that starts in the lining of the ovary, the peritoneum (the tissue lining the abdomen), or the fallopian tubes
  • People whose cancer has been classified as an advanced stage (Stage III or IV)
  • People whose cancer cells test positive for a specific protein called claudin 6 (CLDN6)
  • People whose heart, liver, kidneys, and other organs are functioning at an adequate level

Who may not be able to join:

  • People whose ovarian cancer is of a specific subtype, including clear cell, mucinous, sarcomatous, mixed, low-grade/borderline, or non-epithelial types
  • People who have previously received any systemic (whole-body) treatment for this cancer
  • People who have previously had surgery related to this cancer
  • People who have previously received radiation therapy to the abdomen or pelvis
  • People who have recently received chemotherapy, biological therapies, targeted therapies, or immune-modifying treatments for any condition (confirm with trial site for exact timing details)
  • People who have brain metastases (cancer that has spread to the brain) that are active, getting worse, or causing symptoms
  • People who have serious or uncontrolled medical conditions, active infections, or other significant non-cancer illnesses that may pose health risks
  • People who are currently pregnant or breastfeeding

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 8 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 310-348-9636

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
TORL Biotherapeutics, LLC
Registry
ClinicalTrials.gov
Start date
10 December 2025
Est. completion
1 December 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Characterize the safety and feasibility of TORL-1-23 in combination with chemotherapy by analyzing the incidence of treatment emergent adverse events and serious adverse events.; To assess the efficacy of neoadjuvant TORL-1-23 in combination with chemotherapy

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov