Phase 4 Glaucoma Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with elevated eye pressure (OHT) or mild-to-moderate open-angle glaucoma in both eyes, based on eye tests done within the past year (having one condition in each eye is also acceptable)
• Your eye pressure is between 18 and 34 mmHg in both eyes, either on record or measured at your first visit
• You are able and willing to sign a consent form and follow the study instructions
• You are able to attend all required appointments and cooperate with the eye examinations needed
• If you wear contact lenses, you are willing to remove them at least 24 hours before each study visit
• Your vision (with glasses or lenses if needed) is roughly 20/50 or better in each eye

Who may not be able to join:

• You have very narrow drainage angles, closed-angle glaucoma, a history of angle closure, or have had a laser hole made in your iris (peripheral iridotomy) in either eye
• You have severe glaucoma damage in either eye
• The eye pressure difference between your two eyes is more than 4 mmHg when not using eye pressure-lowering drops
• You have used more than two eye pressure-lowering medications in the 30 days before your screening visit
• You have long-term or repeatedly occurring eye inflammation in either eye
• You have had an eye infection or eye inflammation in either eye within the past 3 months
• You have had a significant eye injury (other than a minor corneal scratch) in either eye within the past 6 months
• You have a significant retinal condition (such as severe diabetic eye disease, certain types of macular degeneration, macular swelling, or a blocked blood vessel in the eye) in either eye
• You have cornea problems that would make accurate eye pressure measurements unreliable (such as scarring, cloudiness, swelling, or keratoconus) in either eye
• You are significantly short-sighted (over -6.00D) or long-sighted (over +2.00D) in either eye
• Your cornea thickness falls outside the range of 480–620 micrometres in either eye
• You have had any previous eye surgery other than a straightforward cataract operation in either eye
• You have had previous glaucoma surgery or certain glaucoma laser treatments in either eye (a specific laser treatment called SLT done more than 6 months ago may be acceptable — confirm with trial site)
• Only one of your eyes has had eye surgery or a glaucoma laser procedure
• You have previously had laser or surgical vision correction (such as LASIK, PRK, or radial keratotomy) in either eye
• You have severe dry eye in either eye
• You have used eye medications in either eye within 30 days of screening (eye pressure-lowering drops may be allowed with a washout period; lubricating dry eye drops are permitted throughout the study)
• You have a known allergy to any ingredient in the study eye drops (such as benzalkonium chloride) or to local anaesthetic eye drops
• You have a significant ongoing health condition that could interfere with the study
• You have taken part in another clinical trial within the 30 days before your screening visit
• Your regular medicines that could affect eye pressure (such as certain blood pressure medications) have changed in the 30 days before screening, or are expected to change during the study
• Other medications known to affect eye pressure (such as steroids, certain blood pressure drugs, water tablets, or blood vessel-widening drugs) have recently changed or are expected to change during the study
• You are a woman who could become pregnant and are currently pregnant, breastfeeding, planning a pregnancy, or not using a medically accepted form of contraception (a negative pregnancy test is required at screening, and you must not intend to become pregnant during the study)
• You have a known allergy or medical reason not to use any of the ingredients in the study medications

Important: Always verify eligibility with the trial site directly before applying.